Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | TACR1 | P25103 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.38 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4961277 | 0.86 | POLB (0.42) | SLC6A4SLC6A2TACR1RXFP1CHRM2 | |
| SCHEMBL4962814 | 0.85 | CHRM2 (0.52) | SLC6A4SLC6A2CHRM2CHRM3KCNH2 | |
| SCHEMBL4963040 | 0.85 | CHRM2 (0.52) | SLC6A4SLC6A2CHRM2CHRM3KCNH2 | |
| SCHEMBL4963973 | 0.83 | REN (0.39) | SLC6A4SLC6A2KCNH2LMNAKDM4E | |
| SCHEMBL4960293 | 0.82 | TRPM8 (0.50) | KCNH2 | |
| SCHEMBL4961872 | 0.80 | SLC6A2 (0.46) | SLC6A4SLC6A2CHRM2CHRM3KCNH2 | |
| SCHEMBL948457 | 0.80 | SLC6A4 (0.48) | MLYCDSLC6A4SLC6A2TACR1KCNH2 | |
| SCHEMBL949410 | 0.80 | SLC6A4 (0.48) | MLYCDSLC6A4SLC6A2TACR1KCNH2 | |
| SCHEMBL948455 | 0.80 | SLC6A4 (0.48) | MLYCDSLC6A4SLC6A2TACR1KCNH2 | |
| SCHEMBL4961286 | 0.79 | SLC6A2 (0.50) | SLC6A4SLC6A2SLC6A1SLC6A11TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1758580-A4 | N-SUBSTITUTED PIPERIDINES AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2008-01-16 | — | — | EP | disclosed |
| EP-1758580-A2 | N-SUBSTITUTED PIPERIDINES AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-03-07 | — | — | EP | disclosed |
| WO-2006012226-A2 | N-SUBSTITUTED PIPERIDINES AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2006-02-02 | — | — | WO | disclosed |