Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | IDH2 | P48735 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4961245 | 0.86 | MLYCD (0.41) | RXFP1TACR1SLC6A2SLC6A4SMN1; SMN2 | |
| SCHEMBL4962731 | 0.84 | TRPM8 (0.41) | POLBRAB9ASLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL4963040 | 0.83 | CHRM2 (0.52) | RAB9ASLC6A2SLC6A4ALDH1A1SMN1; SMN2 | |
| SCHEMBL4962814 | 0.83 | CHRM2 (0.52) | RAB9ASLC6A2SLC6A4ALDH1A1SMN1; SMN2 | |
| SCHEMBL4960546 | 0.81 | MTNR1A (0.44) | POLBRAB9A | |
| SCHEMBL4961286 | 0.77 | SLC6A2 (0.50) | SLC6A2SLC6A4 | |
| SCHEMBL27550043 | 0.77 | POLB (0.50) | POLBRAB9AEPHX2ALDH1A1SMN1; SMN2 | |
| SCHEMBL4963973 | 0.77 | REN (0.39) | SLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL11799330 | 0.75 | ALDH1A1 (0.50) | POLBRAB9AALDH1A1 | |
| SCHEMBL4961292 | 0.75 | CHRM2 (0.48) | RAB9ASLC6A2SLC6A4ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1758580-A4 | N-SUBSTITUTED PIPERIDINES AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2008-01-16 | — | — | EP | claimed |
| EP-1758580-A2 | N-SUBSTITUTED PIPERIDINES AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-03-07 | — | — | EP | claimed |
| WO-2006012226-A2 | N-SUBSTITUTED PIPERIDINES AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2006-02-02 | — | — | WO | claimed |