Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 6/20 | 0.50 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
| ▸ | REN | P00797 | 1/20 | 0.42 |
| ▸ | RPLP1 | P05386 | 2/20 | 0.41 |
| ▸ | RPLP0 | P05388 | 2/20 | 0.41 |
| ▸ | RPS17 | P08708 | 2/20 | 0.41 |
| ▸ | RPSA | P08865 | 2/20 | 0.41 |
| ▸ | RPS2 | P15880 | 2/20 | 0.41 |
| ▸ | RPL35A | P18077 | 2/20 | 0.41 |
| ▸ | RPL7 | P18124 | 2/20 | 0.41 |
| ▸ | RPL17 | P18621 | 2/20 | 0.41 |
| ▸ | RPS4Y1 | P22090 | 2/20 | 0.41 |
| ▸ | RPS3 | P23396 | 2/20 | 0.41 |
| ▸ | RPS12 | P25398 | 2/20 | 0.41 |
| ▸ | RPL13 | P26373 | 2/20 | 0.41 |
| ▸ | RPL10 | P27635 | 2/20 | 0.41 |
| ▸ | RPL12 | P30050 | 2/20 | 0.41 |
| ▸ | RPL9; RPL9P7; RPL9P8; RPL9P9 | P32969 | 2/20 | 0.41 |
| ▸ | RPL22 | P35268 | 2/20 | 0.41 |
| ▸ | RPL4 | P36578 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4960546 | 0.86 | MTNR1A (0.44) | TRPM8CDK9RENNPC1RAB9A | |
| SCHEMBL4961872 | 0.86 | SLC6A2 (0.46) | TRPM8CDK9KCNH2NPC1RAB9A | |
| SCHEMBL4963040 | 0.84 | CHRM2 (0.52) | TRPM8CDK9KCNH2NPC1RAB9A | |
| SCHEMBL4962814 | 0.84 | CHRM2 (0.52) | TRPM8CDK9KCNH2NPC1RAB9A | |
| SCHEMBL4961245 | 0.82 | MLYCD (0.41) | KCNH2 | |
| SCHEMBL25194772 | 0.78 | RPLP1 (0.49) | TRPM8RPLP1RPLP0RPS17RPSA | |
| SCHEMBL4962731 | 0.78 | TRPM8 (0.41) | TRPM8CDK9RENKCNH2NPC1 | |
| Hydrochloric Acid SCHEMBL4000833 | 0.76 | SLC6A2 (0.47) | RPLP1RPLP0RPS17RPSARPS2 | |
| SCHEMBL4961292 | 0.75 | CHRM2 (0.48) | TRPM8CDK9RENRPLP1RPLP0 | |
| SCHEMBL4961968 | 0.75 | LMNA (0.58) | CDK9RPLP1RPLP0RPS17RPSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1758580-A4 | N-SUBSTITUTED PIPERIDINES AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2008-01-16 | — | — | EP | claimed |
| EP-1758580-A2 | N-SUBSTITUTED PIPERIDINES AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-03-07 | — | — | EP | claimed |
| WO-2006012226-A2 | N-SUBSTITUTED PIPERIDINES AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2006-02-02 | — | — | WO | claimed |
| EP-1758580-A4 | N-SUBSTITUTED PIPERIDINES AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2008-01-16 | — | — | EP | disclosed |
| EP-1758580-A2 | N-SUBSTITUTED PIPERIDINES AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-03-07 | — | — | EP | disclosed |
| WO-2006012226-A2 | N-SUBSTITUTED PIPERIDINES AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2006-02-02 | — | — | WO | disclosed |