Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | ERAP2 | Q6P179 | 7/20 | 0.57 |
| ▸ | IL1RN | P18510 | 2/20 | 0.57 |
| ▸ | LNPEP | Q9UIQ6 | 7/20 | 0.54 |
| ▸ | MDM4 | O15151 | 1/20 | 0.54 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.54 |
| ▸ | ERAP1 | Q9NZ08 | 5/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | NPY4R | P50391 | 2/20 | 0.52 |
| ▸ | NPY1R | P25929 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27183038 | 1.00 | TSHR (0.60) | TSHRERAP2IL1RNLNPEPMDM4 | |
| SCHEMBL8214204 | 1.00 | TSHR (0.60) | TSHRERAP2IL1RNLNPEPMDM4 | |
| Hydrochloric Acid SCHEMBL11693250 | 0.99 | TSHR (0.59) | TSHRERAP2IL1RNLNPEPMDM4 | |
| SCHEMBL11759443 | 0.90 | TSHR (0.49) | TSHRERAP2IL1RNLNPEPMDM4 | |
| Aspartame SCHEMBL28591 | 0.90 | ALDH1A1 (0.64) | TSHRALDH1A1THRBCYP2C9CYP2C19 | |
| Aspartame SCHEMBL11085391 | 0.90 | ALDH1A1 (0.64) | TSHRALDH1A1THRBCYP2C9CYP2C19 | |
| Aspartame SCHEMBL900809 | 0.90 | ALDH1A1 (0.64) | TSHRALDH1A1THRBCYP2C9CYP2C19 | |
| Aspartame SCHEMBL3637 | 0.90 | ALDH1A1 (0.64) | TSHRALDH1A1THRBCYP2C9CYP2C19 | |
| Aspartame SCHEMBL8761655 | 0.90 | ALDH1A1 (0.64) | TSHRALDH1A1THRBCYP2C9CYP2C19 | |
| Aspartame SCHEMBL8091203 | 0.90 | ALDH1A1 (0.64) | TSHRALDH1A1THRBCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512435-B1 | Method of crystallizing aspartame | AJINOMOTO KK (JP) | 1997-01-22 | — | — | EP | claimed |
| US-5298648-A | Method of crystallizing aspartame | AJINOMOTO CO., INC. (JP) | 1994-03-29 | — | — | US | claimed |
| EP-0046270-A1 | Novel derivatives of bio-affecting phenolic compounds and pharmaceutical composition containing them | INTERx RESEARCH CORPORATION (US) | 1982-02-24 | — | — | EP | claimed |
| EP-1114828-B1 | N-ALKYLASPARTYLDIPEPTIDE ESTER DERIVATIVES AND SWEETENERS | AJINOMOTO KK (JP) | 2008-03-12 | — | — | EP | disclosed |
| EP-1114828-A1 | N-ALKYLASPARTYLDIPEPTIDE ESTER DERIVATIVES AND SWEETENERS | Ajinomoto Co., Inc. (JP) | 2001-07-11 | — | — | EP | disclosed |
| EP-0512435-B1 | Method of crystallizing aspartame | AJINOMOTO KK (JP) | 1997-01-22 | — | — | EP | disclosed |
| US-5298648-A | Method of crystallizing aspartame | AJINOMOTO CO., INC. (JP) | 1994-03-29 | — | — | US | disclosed |
| EP-0512435-A1 | Method of crystallizing aspartame | Ajinomoto Co., Inc. (JP) | 1992-11-11 | — | — | EP | disclosed |
| US-5001115-A | Prodrugs of biologically active hydroxyaromatic compounds | UNIVERSITY OF FLORIDA (US) | 1991-03-19 | — | — | US | disclosed |
| US-4731412-A | Process and composition for amino-terminal, α-aspartyl and α-glutamyl dipeptide esters | THE SALK INSTITUTE BIOTECHNOLOGY/INDUSTRIAL ASSOCIATES, INC. (US) | 1988-03-15 | — | — | US | disclosed |
| US-4600532-A | Process and composition for amino-terminal, α-aspartyl and α-glutamyl dipeptides and dipeptide esters | THE SALK INSTITUTE BIOTECHNOLOGY/INDUSTRIAL ASSOCIATES, INC. (US) | 1986-07-15 | — | — | US | disclosed |
| EP-0046270-A1 | Novel derivatives of bio-affecting phenolic compounds and pharmaceutical composition containing them | INTERx RESEARCH CORPORATION (US) | 1982-02-24 | — | — | EP | disclosed |
| US-4017472-A | Process for isolation of aspartyl dipeptide esters | G. D. SEARLE & CO. (US) | 1977-04-12 | — | — | US | disclosed |