Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | THRB | P10828 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | ANPEP | P15144 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aspartame SCHEMBL19283498 | 1.00 | ALDH1A1 (0.64) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| Aspartame SCHEMBL10625481 | 1.00 | ALDH1A1 (0.64) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| Aspartame SCHEMBL28591 | 1.00 | ALDH1A1 (0.64) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| Aspartame SCHEMBL900809 | 1.00 | ALDH1A1 (0.64) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| Aspartame SCHEMBL216238 | 1.00 | ALDH1A1 (0.64) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| Aspartame SCHEMBL3637 | 1.00 | ALDH1A1 (0.64) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| Aspartame SCHEMBL10635593 | 1.00 | ALDH1A1 (0.64) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| Aspartame SCHEMBL11085391 | 1.00 | ALDH1A1 (0.64) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| Aspartame SCHEMBL8761655 | 1.00 | ALDH1A1 (0.64) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| Aspartame SCHEMBL3636 | 1.00 | ALDH1A1 (0.64) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109996778-B | Taste modifying aldehydes | 高砂香料工业株式会社 | 2022-12-13 | — | — | CN | claimed |
| EP-0581032-B1 | Method for production of alpha-L-aspartyl-L-phenylalanine methyl ester hydrochloride | AJINOMOTO KK (JP) | 1997-06-11 | — | — | EP | claimed |
| EP-0523813-B1 | Method for crystallizing alpha-L-aspartyl-L-phenylalanine methyl ester | HOLLAND SWEETENER CO (NL) | 1996-11-27 | — | — | EP | claimed |
| US-5304671-A | Solid-liquid separation of suspension; no desalting; precipitation of acid salt; neutralization; hydrolysis | AJINOMOTO CO., INC. (JP) | 1994-04-19 | — | — | US | claimed |
| EP-0581032-A1 | Method for production of alpha-L-aspartyl-L-phenylalanine methyl ester hydrochloride | Ajinomoto Co., Inc. (JP) | 1994-02-02 | — | — | EP | claimed |
| EP-0523813-A1 | Method for crystallizing alpha-L-aspartyl-L-phenylalanine methyl ester | HOLLAND SWEETENER COMPANY V.O.F. (NL) | 1993-01-20 | — | — | EP | claimed |
| EP-0302478-B1 | METHOD FOR PURIFYING A DIPEPTIDE ESTER | Tosoh Corporation (JP) | 1992-05-06 | — | — | EP | claimed |
| US-4944852-A | Method for purifying a dipeptide ester | TOSOH CORPORATION (JP) | 1990-07-31 | — | — | US | claimed |
| US-4831180-A | GRANULATING WET CRYSTALS, DRYING | TOYO SODA MANUFACTURING COMPANY, LTD. (JP) | 1989-05-16 | — | — | US | claimed |
| US-4824994-A | Method for production of N-protected-alpha-L-aspartyl-L-phenylalanine methyl ester | AJINOMOTO CO., INC. (JP) | 1989-04-25 | — | — | US | claimed |
| US-4810818-A | MULTISTAGE DRYING | TOYO SODA MANUFACTURING CO., LTD (JP) | 1989-03-07 | — | — | US | claimed |
| EP-0302478-A1 | Method for purifying a dipeptide ester | Tosoh Corporation (JP) | 1989-02-08 | — | — | EP | claimed |
| EP-0227007-A2 | N-(4-benzyl-L-alpha-aspartyl)-L-phenylalanine methyl ester, its process of preparation and its use | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-07-01 | — | — | EP | claimed |
| US-4638081-A | Process for preparing α-aspartyl-L-phenylalanine methyl ester | DE-BI DERIVATI BIOLOGICI INTERNATIONAL SPA (IT) | 1987-01-20 | — | — | US | claimed |
| JP-5117246-A | — | — | None | — | — | JP | disclosed |
| JP-1040498-A | — | — | None | — | — | JP | disclosed |
| JP-63159355-A | — | — | None | — | — | JP | disclosed |
| US-4549987-A | DEFORMYLATION AND SEPARATION OF N-FORMYL-L-A-ASPARTYL-L-PHENYLALANINE METHYL ESTER | FARMITALIA CARLO ERBA S.P.A. (IT) | 1985-10-29 | — | — | US | disclosed |
| US-4549987-A | DEFORMYLATION AND SEPARATION OF N-FORMYL-L-A-ASPARTYL-L-PHENYLALANINE METHYL ESTER | FARMITALIA CARLO ERBA S.P.A. (IT) | 1985-10-29 | — | — | US | disclosed |
| EP-0132856-A2 | Process for preparing alpha-L-aspartyl-L-phenylalanine methyl ester | DE-BI DERIVATI BIOLOGICI INTERNATIONAL S.p.A. (IT) | 1985-02-13 | — | — | EP | disclosed |