SCHEMBL4962296

SCHEMBL4962296

CSc1ccc2c(c1)CC=[C]N2C

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TRIM24 O15164 3/20 0.33
HTR2A P28223 2/20 0.33
HTR2C P28335 2/20 0.33
HTR2B P41595 1/20 0.33
HTR7 P34969 2/20 0.32
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
HSD17B10 Q99714 1/20 0.32
DRD2 P14416 1/20 0.30
DRD4 P21917 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3585238 0.71 ALDH1A1 (0.35) HTR2AHTR2CHTR2BHTR7ALDH1A1
SCHEMBL19538871 0.68 TRIM24 (0.61) TRIM24ALDH1A1
SCHEMBL20353867 0.60 HTR2A (0.48) TRIM24HTR2AHTR2CHTR2BHTR7
SCHEMBL21947692 0.59 MAOA (0.55) HTR2AHTR2CHTR2BDRD2DRD4
SCHEMBL10563905 0.59 HTR2A (0.34) HTR2AHTR2CHTR2BHTR7ALDH1A1
SCHEMBL4962293 0.59 MCL1 (0.33) ALDH1A1HPGDHSD17B10
SCHEMBL23772573 0.58 NPC1 (0.48) HTR2AHTR2CHTR2BHTR7ALDH1A1
SCHEMBL8483178 0.58 NPC1 (0.44) HTR2AHTR2CHTR2BHTR7ALDH1A1
SCHEMBL8526799 0.58 NOTUM (0.65) HTR2AHTR2CALDH1A1HPGDDRD2
Hydrochloric Acid SCHEMBL10382614 0.58 HTR2A (0.33) HTR2AHTR2CHTR2BHTR7ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1896265-A1 OPTICAL INFORMATION-RECORDING MEDIUM AND INFORMATION-RECORDING METHOD Fujifilm Corporation (JP) 2008-03-12 EP disclosed
WO-2007001095-A1 OPTICAL INFORMATION-RECORDING MEDIUM AND INFORMATION-RECORDING METHOD FUJIFILM CORPORATION (JP) 2007-01-04 WO disclosed