SCHEMBL3585238

SCHEMBL3585238

CN1[C]=CCc2ccccc21

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.35
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
HPGD P15428 1/20 0.35
USP2 O75604 1/20 0.35
CDK4 P11802 1/20 0.35
ALOX15 P16050 1/20 0.35
CCND1 P24385 1/20 0.35
ADRA2C P18825 4/20 0.35
SLC6A2 P23975 4/20 0.35
ADRA2B P18089 3/20 0.35
HTR2A P28223 3/20 0.35
HTR2C P28335 3/20 0.35
SLC6A4 P31645 3/20 0.35
ADRA1A P35348 3/20 0.35
HRH1 P35367 3/20 0.35
HTR2B P41595 3/20 0.35
KCNH2 Q12809 3/20 0.35
ADRA2A P08913 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4966232 0.77 POLB (0.40) SMN1; SMN2DRD2DRD4LMNAOPRK1
SCHEMBL5375189 0.75 NPC1 (0.34) ALDH1A1MEN1KMT2ASMN1; SMN2HPGD
SCHEMBL5396776 0.71 ALDH1A1 (0.32) ALDH1A1MEN1KMT2AUSP2CDK4
SCHEMBL5057450 0.71 SIGMAR1 (0.31)
SCHEMBL5050152 0.71 MGLL (0.30)
SCHEMBL2066994 0.70 ALDH1A1 (0.38) ALDH1A1MEN1KMT2ASMN1; SMN2HPGD
SCHEMBL827824 0.67 ALDH1A1 (0.39) ALDH1A1MEN1KMT2ASMN1; SMN2HPGD
SCHEMBL1450912 0.67 MEN1 (0.44) ALDH1A1MEN1KMT2ASMN1; SMN2USP2
SCHEMBL18634021 0.67 MAOA (0.39) ALDH1A1MEN1KMT2ASMN1; SMN2HPGD
SCHEMBL11572893 0.67 ALDH1A1 (0.39) ALDH1A1MEN1KMT2ASMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 163 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115884773-A Pharmaceutical preparation 詹森药业有限公司 2023-03-31 CN disclosed
EP-3140306-B1 PHOTO-STABLE AND THERMALLY-STABLE DYE COMPOUNDS FOR SELECTIVE BLUE LIGHT FILTERED OPTIC FRONTIER SCIENT INC (US) 2021-11-17 EP disclosed
US-20210026054-A1 PHOTO-STABLE AND THERMALLY-STABLE DYE COMPOUNDS FOR SELECTIVE BLUE LIGHT FILTERED OPTIC FRONTIER SCIENTIFIC INC. 2021-01-28 US disclosed
US-20180259693-A1 PHOTO-STABLE AND THERMALLY-STABLE DYE COMPOUNDS FOR SELECTIVE BLUE LIGHT FILTERED OPTIC FRONTIER SCIENTIFIC, INC. (US) 2018-09-13 US disclosed
US-20170235034-A1 PHOTO-STABLE AND THERMALLY-STABLE DYE COMPOUNDS FOR SELECTIVE BLUE LIGHT FILTERED OPTIC FRONTIER SCIENTIFIC, INC. (US) 2017-08-17 US disclosed
US-9683102-B2 Photo-stable and thermally-stable dye compounds for selective blue light filtered optic FRONTIER SCIENTIFIC, INC. (US) 2017-06-20 US disclosed
EP-3140306-A1 PHOTO-STABLE AND THERMALLY-STABLE DYE COMPOUNDS FOR SELECTIVE BLUE LIGHT FILTERED OPTIC Frontier Scientific, Inc. (US) 2017-03-15 EP disclosed
EP-2104670-B3 NOVEL TRIAZINEDIONE DERIVATIVES AS GABA-B RECEPTOR MODULATORS ADDEX PHARMACEUTICALS SA (CH) 2016-09-21 EP disclosed
EP-2104670-B1 NOVEL TRIAZINEDIONE DERIVATIVES AS GABA-B RECEPTOR MODULATORS ADDEX PHARMACEUTICALS SA (CH) 2016-02-17 EP disclosed
WO-2015171507-A1 PHOTO-STABLE AND THERMALLY-STABLE DYE COMPOUNDS FOR SELECTIVE BLUE LIGHT FILTERED OPTIC FRONTIER SCIENTIFIC, INC. (US) 2015-11-12 WO disclosed
US-5434265-A Inhibitors of HIV protease ELI LILLY AND COMPANY (US) 1995-07-18 US disclosed
WO-1995014017-A1 NON-PEPTIDE TACHYKININ RECEPTOR ANTAGONISTS ELI LILLY AND COMPANY (US) 1995-05-26 WO disclosed
EP-0652009-A1 Identification and use of protease inhibitors ELI LILLY AND COMPANY (US) 1995-05-10 EP disclosed
WO-1995009843-A1 HIV PROTEASE INHIBITORS AGOURON PHARMACEUTICALS, INC. (US) 1995-04-13 WO disclosed
EP-0609625-A1 Inhibitors of HIV protease useful for the treatment of AIDS ELI LILLY AND COMPANY (US) 1994-08-10 EP disclosed
EP-0604184-A1 Inhibitors of HIV protease useful for the treatment of aids ELI LILLY AND COMPANY (US) 1994-06-29 EP disclosed
EP-0604185-A1 Inhibitors of HIV protease useful for the treatment of aids ELI LILLY AND COMPANY (US) 1994-06-29 EP disclosed
EP-0604186-A1 Inhibitors of HIV protease useful for the treatment of aids ELI LILLY AND COMPANY (US) 1994-06-29 EP disclosed
EP-0604182-A2 Inhibitors of HIV protease useful for the treatment of Aids ELI LILLY AND COMPANY (US) 1994-06-29 EP disclosed
EP-0604183-A1 Inhibitors of HIV protease useful for the treatment of aids ELI LILLY AND COMPANY (US) 1994-06-29 EP disclosed