Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 4/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.35 |
| ▸ | ITGB7 | P26010 | 4/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 15/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4010548 | 0.85 | HSD11B1 (0.38) | ITGB1ITGA4ITGB7HSD11B1HDAC4 | |
| SCHEMBL4009205 | 0.83 | ITGB1 (0.38) | ITGB1ITGA4ITGB7HSD11B1HDAC4 | |
| SCHEMBL4005449 | 0.81 | ITGB1 (0.37) | ITGB1ITGA4ITGB7HSD11B1HDAC4 | |
| SCHEMBL4005617 | 0.81 | ITGB1 (0.36) | ITGB1ITGA4ITGB7HSD11B1HDAC4 | |
| SCHEMBL4011653 | 0.81 | HSD11B1 (0.38) | ITGB1ITGA4ITGB7HSD11B1HDAC4 | |
| SCHEMBL4010758 | 0.79 | ALDH1A1 (0.37) | ITGB1ITGA4ITGB7HSD11B1 | |
| SCHEMBL4006571 | 0.79 | HSD11B1 (0.43) | HSD11B1 | |
| SCHEMBL4010678 | 0.78 | HSD11B1 (0.45) | HSD11B1 | |
| SCHEMBL4005139 | 0.78 | ABCB1 (0.38) | ITGB1ITGA4ITGB7HSD11B1 | |
| SCHEMBL4299977 | 0.78 | KMT2A (0.39) | ITGB1ITGA4ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773780-A4 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2008-01-09 | — | — | EP | claimed |
| EP-1773780-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-04-18 | — | — | EP | claimed |
| WO-2006012227-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2006-02-02 | — | — | WO | claimed |