Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAT | P00750 | 1/20 | 0.35 |
| ▸ | NMT1 | P30419 | 1/20 | 0.30 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4965409 | 0.73 | GABRA1 (0.40) | — | |
| SCHEMBL4963859 | 0.73 | GABRA1 (0.44) | HTR6 | |
| SCHEMBL3853174 | 0.62 | GRIN1 (0.52) | PLATNMT1 | |
| SCHEMBL13619754 | 0.60 | PDE10A (0.41) | PLATNMT1 | |
| SCHEMBL24959717 | 0.60 | HRH4 (0.42) | — | |
| SCHEMBL4965972 | 0.60 | HTR6 (0.44) | PLATHTR6 | |
| SCHEMBL4303824 | 0.60 | TNKS (0.37) | — | |
| SCHEMBL6160094 | 0.60 | TLR9 (0.36) | PLATHTR6 | |
| SCHEMBL4960528 | 0.57 | HTR2C (0.39) | PLAT | |
| SCHEMBL4301980 | 0.57 | GABRA1 (0.34) | PLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904483-A1 | BENZIMIDAZOLE DERIVATIVES AS 5-HT6,5-HT24 | F. Hoffmann-Roche AG (CH) | 2008-04-02 | — | — | EP | claimed |
| WO-2007006677-A1 | BENZIMIDAZOLE DERIVATIVES AS 5-HT6,5-HT24 | F. HOFFMANN-LA ROCHE AG (CH) | 2007-01-18 | — | — | WO | claimed |