Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | OGA | O60502 | 8/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4959701 | 0.84 | LMNA (0.47) | LMNAMAPTMEN1KMT2AOGA | |
| SCHEMBL4960772 | 0.83 | LMNA (0.45) | LMNAMAPTMEN1KMT2APOLB | |
| SCHEMBL4962537 | 0.77 | LMNA (0.44) | LMNAMAPTMEN1KMT2AOGA | |
| SCHEMBL1236714 | 0.73 | PIK3CG (0.50) | MAPT | |
| SCHEMBL4965155 | 0.72 | OGA (0.43) | LMNAMAPTMEN1KMT2AOGA | |
| SCHEMBL4973460 | 0.67 | LMNA (0.47) | LMNAMAPTMEN1KMT2AOGA | |
| SCHEMBL4672859 | 0.64 | LMNA (0.53) | LMNAMAPTMEN1KMT2AOGA | |
| SCHEMBL1236497 | 0.64 | PIK3CG (0.56) | MAPTMEN1KMT2APOLB | |
| SCHEMBL12523827 | 0.64 | LMNA (0.55) | LMNAMAPTMEN1KMT2AOGA | |
| SCHEMBL233711 | 0.64 | CDK2 (0.60) | LMNAMAPTMEN1KMT2AOGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1885716-A1 | THIAZOLE DERIVATIVES AND USE THEREOF | Laboratoires Serono SA (CH) | 2008-02-13 | — | — | EP | disclosed |
| WO-2006125803-A1 | THIAZOLE DERIVATIVES AND USE THEREOF | LABORATOIRES SERONO S.A. (CH) | 2006-11-30 | — | — | WO | disclosed |