Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 13/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1237592 | 0.83 | OGA (0.45) | OGAOPRK1LMNAMAPTKMT2A | |
| SCHEMBL1235241 | 0.76 | PIK3CG (0.52) | LMNAMAPTKMT2APIK3CGUSP2 | |
| SCHEMBL4672859 | 0.73 | LMNA (0.53) | OGALMNAMAPTKMT2AMEN1 | |
| SCHEMBL4960521 | 0.72 | LMNA (0.45) | OGAOPRK1LMNAMAPTKMT2A | |
| SCHEMBL4964973 | 0.72 | LMNA (0.47) | OGALMNAMAPTKMT2AMEN1 | |
| SCHEMBL4959701 | 0.72 | LMNA (0.47) | OGALMNAMAPTKMT2AMEN1 | |
| SCHEMBL4960772 | 0.70 | LMNA (0.45) | LMNAMAPTKMT2AMEN1PIK3CG | |
| SCHEMBL1236816 | 0.70 | PIK3CG (0.47) | LMNAKMT2APIK3CGUSP2TSHR | |
| SCHEMBL4962537 | 0.69 | LMNA (0.44) | OGALMNAMAPTKMT2AMEN1 | |
| SCHEMBL1235188 | 0.67 | PIK3CG (0.51) | LMNAKMT2APIK3CGUSP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1885716-A1 | THIAZOLE DERIVATIVES AND USE THEREOF | Laboratoires Serono SA (CH) | 2008-02-13 | — | — | EP | disclosed |
| WO-2006125803-A1 | THIAZOLE DERIVATIVES AND USE THEREOF | LABORATOIRES SERONO S.A. (CH) | 2006-11-30 | — | — | WO | disclosed |