Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27723625 | 0.84 | HTR2A (0.40) | — | |
| SCHEMBL4713338 | 0.80 | GPBAR1 (0.34) | TDP2PDE3BPDE3A | |
| SCHEMBL4794338 | 0.79 | MAPK14 (0.41) | TDP2 | |
| SCHEMBL4607974 | 0.78 | AQP1 (0.32) | PDE3BPDE3A | |
| SCHEMBL4596615 | 0.77 | AQP1 (0.39) | — | |
| SCHEMBL4608351 | 0.73 | AQP1 (0.42) | — | |
| SCHEMBL5586497 | 0.73 | AQP1 (0.54) | — | |
| SCHEMBL4712016 | 0.73 | AQP1 (0.40) | CNR1 | |
| SCHEMBL4712018 | 0.73 | AQP1 (0.40) | PDE3BPDE3ACTSD | |
| SCHEMBL4609617 | 0.72 | AQP1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1898895-A2 | TREATMENT OF DRUG ABUSE | Wyeth (US) | 2008-03-19 | — | — | EP | disclosed |
| WO-2006116148-A2 | (7-ARLYSUBSTITUTED 2, 3-DIHYDR0-1-BENZ0FURAN-2-YL) ALKYLAMINES IN THE TREATMENT' OF SUBSTANCE ABUSE | WYETH (US) | 2006-11-02 | — | — | WO | disclosed |