SCHEMBL4965074

SCHEMBL4965074

Cc1ccc(-n2c(=O)n(-c3ccc(C)c(N)c3)c(=O)n(-c3ccc(C)c(N)c3)c2=O)cc1N

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.56
MEN1 O00255 6/20 0.56
KMT2A Q03164 6/20 0.56
KDM4E B2RXH2 4/20 0.56
NPSR1 Q6W5P4 2/20 0.56
ALDH1A1 P00352 5/20 0.46
TDP1 Q9NUW8 2/20 0.46
CASP1 P29466 2/20 0.46
CYP3A4 P08684 3/20 0.43
ATAD2 Q6PL18 1/20 0.42
THRB P10828 1/20 0.42
GAA P10253 3/20 0.41
LMNA P02545 1/20 0.41
TSHR P16473 3/20 0.41
RAD52 P43351 1/20 0.40
NPC1 O15118 5/20 0.38
RAB9A P51151 3/20 0.38
MAPK1 P28482 2/20 0.38
HPGD P15428 1/20 0.37
MCL1 Q07820 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22383909 0.94 MAPT (0.51) MAPTMEN1KMT2AKDM4ENPSR1
SCHEMBL17636557 0.80 ALDH1A1 (0.52) MAPTMEN1KMT2AKDM4ENPSR1
SCHEMBL10454214 0.80 ALDH1A1 (0.50) MAPTMEN1KMT2AKDM4ENPSR1
SCHEMBL11192658 0.76 MEN1 (0.50) MAPTMEN1KMT2AKDM4ENPSR1
SCHEMBL6519759 0.76 MAPT (0.49) MAPTMEN1KMT2AKDM4ENPSR1
SCHEMBL9624054 0.75 L3MBTL1 (0.55) MAPTMEN1KMT2AALDH1A1CYP3A4
SCHEMBL3343075 0.73 ATAD2 (0.46) MAPTMEN1KMT2AKDM4ENPSR1
SCHEMBL22593825 0.72 ALKBH5 (0.36) MAPTMEN1KMT2AKDM4ENPSR1
SCHEMBL11864269 0.72 MEN1 (0.72) MEN1KMT2ANPSR1ALDH1A1CASP1
SCHEMBL6522042 0.72 MAPT (0.43) MAPTMEN1KMT2AKDM4ENPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7470451-B2 Binding agent component for surface coating agents with improved adhesive properties HENKEL AG & CO. KGAA (DE) 2008-12-30 US disclosed
US-20060247407-A1 Polymers with urea groups and silyl groups and production and use thereof HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) 2006-11-02 US disclosed
US-7057001-B2 Polymers with urea groups and silyl groups and production and use thereof HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 2006-06-06 US disclosed
US-20050260401-A1 Polymers with urea groups and silyl groups and production and use thereof HENKEL AG & CO. KGAA (DE) 2005-11-24 US disclosed
US-20050129955-A1 Binding agent component for surface coating agents with improved adhesive properties HENKEL AG & CO. KGAA (DE) 2005-06-16 US disclosed
US-5705594-A Polyamine crosslinking agent formulation and its preparation BAYER AKTIENGESELLSCHAFT (DE) 1998-01-06 US disclosed
EP-0274646-B1 PROCESS FOR THE PREPARATION OF PREPREGS, AND THEIR USE Siemens Nixdorf Informationssysteme Aktiengesellschaft (DE) 1992-02-05 EP disclosed
US-4812490-A POLYEPOXY RESIN, TRIAZINE HARDENER, MINERAL FILLER FOR ENCAPSULATING SEMICONDUCTOR COMPONENTS SIEMENS AKTIENGESELLSCHAFT (DE) 1989-03-14 US disclosed
US-4783345-A Method for the manufacture of prepregs and their use SIEMENS AKTIENGESELLSCHAFT (DE) 1988-11-08 US disclosed
EP-0274646-A1 Process for the preparation of prepregs, and their use Siemens Nixdorf Informationssysteme Aktiengesellschaft (DE) 1988-07-20 EP disclosed
EP-0271772-A2 Epoxy resin molding compounds SIEMENS AKTIENGESELLSCHAFT (DE) 1988-06-22 EP disclosed
US-4728697-A DIELECTRIC COATINGS FOR METAL CONDUCTORS GENERAL ELECTRIC COMPANY (US) 1988-03-01 US disclosed
EP-0223958-A2 Crosslinked copolyamideimides and method for their preparation GENERAL ELECTRIC COMPANY (US) 1987-06-03 EP disclosed