Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 3/20 | 0.48 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 5/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.41 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.41 |
| ▸ | GYS1 | P13807 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4629897 | 0.84 | LPAR1 (0.53) | LPAR1LPAR5MAOBSCN9AALOX5 | |
| Tert-Butylamine SCHEMBL5309305 | 0.80 | LPAR1 (0.49) | LPAR1LPAR5MAOBSCN9AALOX5 | |
| SCHEMBL4630536 | 0.78 | LPAR1 (0.51) | LPAR1LPAR5MAOBPTPN1 | |
| SCHEMBL3997798 | 0.77 | TRPM8 (0.52) | LPAR1LPAR5MAOBPARP15PARP14 | |
| Amantadine SCHEMBL5313198 | 0.74 | LPAR1 (0.43) | LPAR1LPAR5MAOBSCN9AALOX5 | |
| SCHEMBL4629905 | 0.74 | LPAR1 (0.46) | LPAR1LPAR5MAOBSCN9AALOX5 | |
| SCHEMBL2552269 | 0.74 | FOLH1 (0.53) | ALOX5PTPN1 | |
| SCHEMBL5989548 | 0.74 | RXRA (0.59) | L3MBTL1PTPN1 | |
| Methane SCHEMBL10567951 | 0.73 | FOLH1 (0.52) | ALOX5PTPN1 | |
| SCHEMBL4430140 | 0.72 | NPC1 (0.52) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1517883-B1 | ORTHO-SUBSTITUTED BENZOIC ACID DERIVATIVES FOR THE TREATMENT OF INSULIN RESISTANCE | ASTRAZENECA AB (SE) | 2008-02-13 | — | — | EP | claimed |