Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 5/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 2/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28428597 | 0.75 | PTGS1 (0.39) | PTGS1PTGS2PTPN1CA2CA1 | |
| SCHEMBL18195885 | 0.73 | KMT2A (0.47) | PTGS1PTGS2PTPN1CA2CA1 | |
| SCHEMBL4565158 | 0.72 | PGR (0.50) | PTGS1PTGS2CA2CA1CA9 | |
| SCHEMBL780030 | 0.72 | CA1 (0.56) | PTGS1PTGS2CA2CA1CA9 | |
| SCHEMBL8821206 | 0.72 | CA1 (0.56) | PTGS1PTGS2CA2CA1CA9 | |
| SCHEMBL9231998 | 0.71 | PGR (0.52) | CA2CA1PGRMEN1KMT2A | |
| SCHEMBL6001500 | 0.71 | PTPN1 (0.86) | PTGS1PTGS2PTPN1CA2PGR | |
| SCHEMBL29098407 | 0.71 | ALDH1A1 (0.42) | PTGS1PTGS2PTPN1MEN1KMT2A | |
| SCHEMBL15543670 | 0.71 | MEN1 (0.53) | PTGS1PTGS2PTPN1MEN1KMT2A | |
| SCHEMBL1128833 | 0.70 | CA1 (0.54) | PTGS1PTGS2CA2CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1890547-A2 | CONTROL OF PARASITES IN ANIMALS BY N-[(PHENYLOXY)PHENYL]-1,1,1-TRIFLUOROMETHANESULFONAMIDE AND N-[(PHENYLSULFANYL)PHENYL]-1,1,1-TRIFLUOROMETHANESULFONAMIDE DERIVATIVES | Schering-Plough Ltd. (CH) | 2008-02-27 | — | — | EP | disclosed |
| WO-2006135648-A2 | CONTROL OF PARASITES IN ANIMALS BY N-[(PHENYLOXY)PHENYL]-1,1,1-TRIFLUOROMETHANESULFONAMIDE AND N-[(PHENYLSULFANYL)PHENYL]-1,1,1-TRIFLUOROMETHANESULFONAMIDE DERIVATIVES | SCHERING-PLOUGH LTD. (CH) | 2006-12-21 | — | — | WO | disclosed |