Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.48 |
| ▸ | IL1RN | P18510 | 1/20 | 0.48 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NAT1 | P18440 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28743010 | 0.87 | FFAR1 (0.54) | PGRCA1CA2MMP1MMP2 | |
| SCHEMBL4869139 | 0.85 | PGR (0.60) | PGRCA1CA2MMP1MMP2 | |
| SCHEMBL7830783 | 0.82 | CA2 (0.59) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL10529091 | 0.79 | CA1 (0.56) | PGRCA1CA2MMP1MMP2 | |
| Hydrochloric Acid SCHEMBL6621709 | 0.78 | PGR (0.52) | PGRCA1CA2MMP1MMP2 | |
| SCHEMBL4565158 | 0.76 | PGR (0.50) | PGRCA1CA2MMP1KEAP1 | |
| SCHEMBL366135 | 0.76 | CA2 (0.52) | PGRCA1CA2MMP1MMP2 | |
| SCHEMBL2229037 | 0.74 | CYP2D6 (0.51) | ALDH1A1MEN1KMT2AKDM4EHTR6 | |
| SCHEMBL7992098 | 0.74 | KMT2A (0.34) | PGRCA1CA2ALDH1A1MEN1 | |
| SCHEMBL7995667 | 0.74 | CCR2 (0.38) | PGRCA1CA2ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1103866-A | Nes pesticides | RHONE POULENC AGRICULTURE (GB) | 1995-06-21 | — | — | CN | claimed |
| EP-0634404-A1 | Phtalazin derivatives and their use as pesticides | RHONE POULENC AGRICULTURE LTD. (GB) | 1995-01-18 | — | — | EP | claimed |
| CN-1103866-A | Nes pesticides | RHONE POULENC AGRICULTURE (GB) | 1995-06-21 | — | — | CN | disclosed |
| EP-0634404-A1 | Phtalazin derivatives and their use as pesticides | RHONE POULENC AGRICULTURE LTD. (GB) | 1995-01-18 | — | — | EP | disclosed |