SCHEMBL4565158

SCHEMBL4565158

CS(=O)(=O)NOc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.50
KEAP1 Q14145 1/20 0.46
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA9 Q16790 2/20 0.41
KMT2A Q03164 4/20 0.40
HTT P42858 3/20 0.40
MEN1 O00255 3/20 0.40
PTGS1 P23219 2/20 0.40
PTGS2 P35354 2/20 0.40
HPGD P15428 3/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
NPC1 O15118 1/20 0.40
AR P10275 1/20 0.40
RAB9A P51151 1/20 0.40
CA4 P22748 1/20 0.39
CCNA2 P20248 1/20 0.38
CDK2 P24941 1/20 0.38
CCNA1 P78396 1/20 0.38
CDK5 Q00535 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27575208 0.79 CA2 (0.54) PGRCA1CA2CA9KMT2A
SCHEMBL29092781 0.77 PGR (0.46) PGRKEAP1CA1CA2CA9
SCHEMBL9231998 0.76 PGR (0.52) PGRKEAP1CA1CA2KMT2A
SCHEMBL26704607 0.75 CA1 (0.52) CA1CA2CA9KMT2AMEN1
SCHEMBL29290860 0.74 PGR (0.43) PGRKEAP1CA1CA2CA9
SCHEMBL28395229 0.72 CA1 (0.51) CA1CA2CA9KMT2AHTT
SCHEMBL4965686 0.72 PTGS1 (0.44) PGRCA1CA2CA9KMT2A
SCHEMBL4869139 0.71 PGR (0.60) PGRKEAP1CA1CA2KMT2A
SCHEMBL3069934 0.71 SMN1; SMN2 (0.52) KMT2AHTTMEN1HPGDSMN1; SMN2
Anisole SCHEMBL9269922 0.70 CA4 (0.67) PGRCA1CA2KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9963560-B2 Process for dispersing particles in filled resin compositions ARISDYNE SYSTEMS, INC. (US) 2018-05-08 US disclosed
EP-3212314-A1 PROCESS FOR DISPERSING PARTICLES IN FILLED RESIN COMPOSITIONS Arisdyne Systems, Inc. (US) 2017-09-06 EP disclosed
WO-2016069220-A1 PROCESS FOR DISPERSING PARTICLES IN FILLED RESIN COMPOSITIONS ARISDYNE SYSTEMS, INC. (US) 2016-05-06 WO disclosed
US-20160122479-A1 PROCESS FOR DISPERSING PARTICLES IN FILLED RESIN COMPOSITIONS ARISDYNE SYSTEMS, INC. 2016-05-05 US disclosed
EP-2992057-A1 PROCESS FOR PREPARING POLY(BENZOXAZINES) 3M Innovative Properties Company (US) 2016-03-09 EP disclosed
WO-2014179100-A1 PROCESS FOR PREPARING POLY(BENZOXAZINES) 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-11-06 WO disclosed
EP-2064268-A2 METHOD OF CHANGING RHEOLOGY IN FILLED RESIN SYSTEMS USING CAVITATION National Starch and Chemical Investment Holding Corporation (US) 2009-06-03 EP disclosed
WO-2008066995-A2 METHOD OF CHANGING RHEOLOGY IN FILLED RESIN SYSTEMS USING CAVITATION HENKEL CORPORATION (US) 2008-06-05 WO disclosed
WO-2000000535-A1 CATIONIC RING-OPENING POLYMERIZATION OF BENZOXAZINES EDISON POLYMER INNOVATION CORPORATION (US) 2000-01-06 WO disclosed