SCHEMBL4965996

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4969666	0.90	EPHX2 (0.41)	EPHX2HDAC4NPC1RAB9ARORC
	SCHEMBL14493794	0.86	RHOA (0.43)	EPHX2
	SCHEMBL4967009	0.81	BDKRB1 (0.31)	EPHX2HDAC4BDKRB1
	SCHEMBL4967016	0.81	BDKRB1 (0.31)	EPHX2HDAC4BDKRB1
	SCHEMBL981548	0.76	EPHX2 (0.40)	EPHX2HDAC4NPC1RAB9AALDH1A1
	SCHEMBL4967217	0.76	IMPDH2 (0.46)	EPHX2HDAC4NPC1RAB9AALDH1A1
	SCHEMBL986328	0.73	NR3C1 (0.40)	EPHX2POLBMEN1KMT2A
	SCHEMBL4966906	0.72	EPHX2 (0.33)	EPHX2HDAC4BDKRB1POLBMEN1
	SCHEMBL4966914	0.72	EPHX2 (0.33)	EPHX2HDAC4BDKRB1POLBMEN1
	SCHEMBL4966794	0.72	RHOA (0.40)	EPHX2HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.