SCHEMBL4966489

SCHEMBL4966489

O=P(O)(O)CCNCCP(=O)(O)O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYMS P04818 1/20 0.53
S1PR2 O95136 6/20 0.52
S1PR4 O95977 6/20 0.52
S1PR1 P21453 6/20 0.52
S1PR3 Q99500 6/20 0.52
S1PR5 Q9H228 1/20 0.52
ALDH1A1 P00352 1/20 0.47
PGK1 P00558 1/20 0.44
PGK2 P07205 1/20 0.44
LMNA P02545 1/20 0.43
CYP3A4 P08684 1/20 0.43
NFKB1 P19838 1/20 0.43
BLM P54132 1/20 0.43
PMP22 Q01453 1/20 0.43
GRIN2D O15399 1/20 0.43
GRIN3B O60391 1/20 0.43
GRIN1 Q05586 1/20 0.43
GRIN2A Q12879 1/20 0.43
GRIN2B Q13224 1/20 0.43
GRIN2C Q14957 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2045907 0.88 S1PR2 (0.45) TYMSS1PR2S1PR4S1PR1S1PR3
SCHEMBL1479560 0.86 LMNA (0.59) TYMSS1PR2S1PR4S1PR1S1PR3
SCHEMBL9792362 0.86 TYMS (0.48) TYMSS1PR2S1PR4S1PR1S1PR3
SCHEMBL5595395 0.86 S1PR2 (0.59) TYMSS1PR2S1PR4S1PR1S1PR3
SCHEMBL17833159 0.86 S1PR2 (0.43) TYMSS1PR2S1PR4S1PR1S1PR3
SCHEMBL16625434 0.86 S1PR2 (0.43) TYMSS1PR2S1PR4S1PR1S1PR3
SCHEMBL8768407 0.84
Hydrochloric Acid SCHEMBL5985877 0.84 S1PR2 (0.57) TYMSS1PR2S1PR4S1PR1S1PR3
SCHEMBL744518 0.83
SCHEMBL1479644 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1902078-A1 (METH)ACRYLAMIDE PHOSPHORUS MONOMER COMPOSITION Ciba Specialty Chemicals Holding, Inc. (CH) 2008-03-26 EP disclosed
WO-2007006648-A1 (METH)ACRYLAMIDE PHOSPHORUS MONOMER COMPOSITION CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2007-01-18 WO disclosed
EP-0743059-B1 Antibacterial oral composition for applying to dental implant areas COLGATE PALMOLIVE CO (US) 2002-12-04 EP disclosed
US-6096293-A APPLYING ORAL COMPOSITION CONTAINING 2,4-DI-TERT-BUTYL PHENOL TO TEETH COLGATE-PALMOLIVE COMPANY (US) 2000-08-01 US disclosed
US-5912274-A WATER INSOLUBLE NONCATIONIC ANTIBACTERIAL PHENOL CONTAINING, RELATIVE TO THE HYDROXYL GROUP, AN ALKYL OR CYCLOALKYL GROUP, PREFERABLY TERT.-BUTYL (T-BUTYL), IN THE 2-POSITION, AND SUBSTITUENTS IN ONE OR BOTH OF THE 4- AND 5-POSITIONS COLGATE-PALMOLIVE COMPANY (US) 1999-06-15 US disclosed
EP-0852486-A2 ANTIPLAQUE ORAL COMPOSITION Colgate-Palmolive Company (US) 1998-07-15 EP disclosed
US-5776435-A DENTIFRICES COLGATE-PALMOLIVE COMPANY (US) 1998-07-07 US disclosed
US-5728756-A BETA-STYRENEPHOSPHONIC ACID-VINYL PHOSPHONIC ACID COPOLYMER FOR ANTIPLAQUE COLGATE PALMOLIVE COMPANY (US) 1998-03-17 US disclosed
US-5723500-A WATER INSOLUBLE, NONCATIONIC, ANTIBACTERIAL, STERICALLY HINDERED PHENOL; MOUTHWASHES, DENTIFRICES COLGATE-PALMOLIVE COMPANY (US) 1998-03-03 US disclosed
US-5686064-A MIXTURE INCLUDES TETRAALKALI METAL POLYPHOSPHATE AND TRICLOSAN; DENTIFRICES COLGATE PALMOLIVE COMPANY (US) 1997-11-11 US disclosed
US-5294431-A Aqueous vehicle, noncationic bactericide, surfactant, flavoring oil, alcohol and a bactericide promoter enhancing delivery and adhesion; phosphate-free COLGATE-PALMOLIVE CO. (US) 1994-03-15 US disclosed
US-5292526-A Macroemulsion of non-cationic antibacterial agent COLGATE-PALMOLIVE CO. (US) 1994-03-08 US disclosed
US-5288480-A Antiplaque antibacterial oral composition COLGATE-PALMOLIVE CO. (US) 1994-02-22 US disclosed
US-5275805-A Inhibitors of plaque in mouths with mixtures of salicylanilide and nonionic surfactants COLGATE-PALMOLIVE CO. 1994-01-04 US disclosed
US-5192530-A Solubilizer, enhancing agent to aid retention, and delivery enhancement COLGATE-PALMOLIVE COMPANY (US) 1993-03-09 US disclosed
US-5192531-A Triclosan as a water insoluble noncationic additive for dentifrices COLGATE-PALMOLIVE COMPANY (US) 1993-03-09 US disclosed
US-5188821-A ANTIBACTERIAL ANTIPLAQUE ORAL COMPOSITION MOUTHWASH OR LIQUID DENTIFRICE COLGATE-PALMOLIVE COMPANY (US) 1993-02-23 US disclosed
US-5180578-A Adhesion to oral surfaces COLGATE-PALMOLIVE COMPANY (US) 1993-01-19 US disclosed
US-5178851-A Dentifrices treatment with triclosan and carriers COLGATE-PALMOLIVE COMPANY (US) 1993-01-12 US disclosed
US-5032386-A Dentistry COLGATE-PALMOLIVE COMPANY (US) 1991-07-16 US disclosed