SCHEMBL496749

SCHEMBL496749

O=S(=O)(O)Cc1ccc(Cl)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
KDM4E B2RXH2 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
GABBR2 O75899 1/20 0.44
GABBR1 Q9UBS5 1/20 0.44
ALDH1A1 P00352 3/20 0.44
NPC1 O15118 1/20 0.44
CYP3A4 P08684 2/20 0.43
EGFR P00533 1/20 0.43
ERBB2 P04626 1/20 0.43
CYP1A2 P05177 1/20 0.43
TSHR P16473 1/20 0.43
MAPT P10636 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
HPGD P15428 1/20 0.42
HSD17B10 Q99714 1/20 0.42
MAPK1 P28482 1/20 0.42
IDO1 P14902 1/20 0.42
BCHE P06276 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28259963 0.98 MEN1 (0.47) MEN1KMT2AKDM4EL3MBTL1GABBR2
SCHEMBL8474031 0.87 CA2 (0.41) KMT2AKDM4ECYP1A2TSHRMAPT
SCHEMBL1194611 0.80 KMT2A (0.52) MEN1KMT2AKDM4EL3MBTL1ALDH1A1
SCHEMBL925715 0.78 KMT2A (0.50) MEN1KMT2AKDM4EL3MBTL1ALDH1A1
SCHEMBL9162919 0.78 KMT2A (0.50) MEN1KMT2AKDM4EL3MBTL1ALDH1A1
SCHEMBL4371994 0.78 ABAT (0.50) KDM4EL3MBTL1ALDH1A1CYP3A4HPGD
SCHEMBL259654 0.78 CA2 (0.52) TSHR
SCHEMBL29581044 0.77 PNMT (0.54) KMT2ACYP3A4IDO1
SCHEMBL3135932 0.77 TAAR1 (0.46) MEN1KMT2AGABBR2GABBR1
SCHEMBL294676 0.77 PNMT (0.54) KMT2ACYP3A4IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115558336-A Ink layer material suitable for thermal transfer printing intelligent printing carbon ribbon and preparation method thereof 福建鸣友新材料科技有限公司 2023-01-03 CN claimed
US-20150322094-A1 USE OF SUBSTITUTED 2,3-DIHYDRO-1-BENZOFURAN-4-CARBOXYLIC ACIDS OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AG (DE) 2015-11-12 US claimed
EP-2578577-A1 Sulfonyl esters of tetrahydrocannabinol and derivatives thereof Albany Molecular Research, Inc. (US) 2013-04-10 EP claimed
US-7674922-B2 Process for production of delta-9-tetrahydrocannabinol ALBANY MOLECULAR RESEARCH, INC. (US) 2010-03-09 US claimed
EP-1928853-A2 PROCESS FOR PRODUCTION OF DELTA-9-TETRAHYDROCANNABINOL AMR Technology, Inc. (US) 2008-06-11 EP claimed
EP-0816347-B1 Ammonium oxazole- and amino oxazolium intermediates, methods for their preparation and their use in the manufacture of insecticidal, acaricidal and nematocidal arylpyrrole derivatives BASF AG (DE) 2007-06-20 EP claimed
US-20070093665-A1 Process for production of delta-9- tetrahydrocannabinol AMR TECHNOLOGY, INC. (US) 2007-04-26 US claimed
CN-1311835-C Parenteral pharmaceutical composition containing bisphosphonates HOFFMANN LA ROCHE (CH) 2007-04-25 CN claimed
WO-2007041167-A2 PROCESS FOR PRODUCTION OF DELTA-9-TETRAHYDROCANNABINOL AMR TECHNOLOGY, INC. (US) 2007-04-12 WO claimed
CN-1396830-A Parenteral pharmaceutical composition containing bisphosphonates HOFFMANN LA ROCHE (CH) 2003-02-12 CN claimed
US-20250020997-A1 PHOTORESIST COMPOSITIONS AND METHODS OF MANUFACTURING INTEGRATED CIRCUIT DEVICES USING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2025-01-16 US disclosed
CN-117774534-A High-temperature-resistant solvent-resistant thermal transfer carbon ribbon and manufacturing method and application thereof 安徽壹敏新材料有限公司 2024-03-29 CN disclosed
US-11897857-B2 Isotopically-stabilized tetronimide compounds MIDWESTERN UNIVERSITY (US) 2024-02-13 US disclosed
CN-115558336-A Ink layer material suitable for thermal transfer printing intelligent printing carbon ribbon and preparation method thereof 福建鸣友新材料科技有限公司 2023-01-03 CN disclosed
US-20210094927-A1 ISOTOPICALLY-STABILIZED TETRONIMIDE COMPOUNDS MIDWESTERN UNIVERSITY 2021-04-01 US disclosed
EP-0414018-A2 Process for the preparation of dehydrocycloclausenamide and its derivatives in the racemic form and as optically active (+)- or (-)-enantiomers BAYER AG (DE) 1991-02-27 EP disclosed
EP-0240015-A2 Carbostyril derivatives, process for preparing them, pharmaceutical composition, and use OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1987-10-07 EP disclosed
US-4415574-A BACTERICIDES; MEDICINES; POTENTIATION OF SULFA DRUGS S. A. PANMEDICA (FR) 1983-11-15 US disclosed
US-4139530-A CATIONIC DYES BAYER AKTIENGESELLSCHAFT (DE) 1979-02-13 US disclosed
US-3934010-A MITICIDE CIBA-GEIGY CORPORATION (US) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11897857-B2 Isotopically-stabilized tetronimide compounds ASPH, BACE1, DNPEP MEN1 2521/4885KMT2A 737/4885KDM4E 925/4885
US-20150322094-A1 USE OF SUBSTITUTED 2,3-DIHYDRO-1-BENZOFURAN-4-CARBOXYLIC ACIDS OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS CAT, HSF1, HPD MEN1 4785/4885KMT2A 3258/4885KDM4E 2664/4885
US-20070093665-A1 Process for production of delta-9- tetrahydrocannabinol CNR2, CNR1, HRH4 MEN1 4004/4885KMT2A 2043/4885KDM4E 2374/4885
US-20210094927-A1 ISOTOPICALLY-STABILIZED TETRONIMIDE COMPOUNDS ASPH, BACE1, DNPEP MEN1 2521/4885KMT2A 737/4885KDM4E 925/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.