SCHEMBL496801

SCHEMBL496801

FC(F)(F)C(Oc1ccccc1)(Oc1ccccc1)C(F)(F)F

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.41
TSHR P16473 2/20 0.41
ALDH1A1 P00352 1/20 0.38
CA4 P22748 1/20 0.38
KCNA3 P22001 1/20 0.35
CCR6 P51684 1/20 0.34
KCNH2 Q12809 1/20 0.34
MLYCD O95822 1/20 0.33
CA5A P35218 1/20 0.33
CA5B Q9Y2D0 1/20 0.33
KIF11 P52732 1/20 0.33
POLB P06746 1/20 0.33
PDK1 Q15118 1/20 0.33
PDK2 Q15119 1/20 0.33
PDK3 Q15120 1/20 0.33
PDK4 Q16654 1/20 0.33
GRIN2B Q13224 1/20 0.33
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24615573 0.79 LTA4H (0.41) LTA4HTSHRALDH1A1CA4KCNA3
SCHEMBL10604957 0.79 TSHR (0.41) LTA4HTSHRALDH1A1CA4KCNA3
SCHEMBL6000951 0.79 LTA4H (0.41) LTA4HTSHRALDH1A1CA4KCNA3
SCHEMBL168125 0.78 KIF11 (0.47) LTA4HTSHRCCR6KCNH2KIF11
SCHEMBL19747191 0.77 LMNA (0.31) CA4CCR6KCNH2
SCHEMBL29087324 0.76 KIF11 (0.46) LTA4HTSHRCCR6KCNH2KIF11
Fluoride SCHEMBL28371495 0.76 KIF11 (0.46) LTA4HTSHRCCR6KCNH2KIF11
SCHEMBL4036809 0.76 KIF11 (0.46) LTA4HTSHRCCR6KCNH2KIF11
Ammonia Solution, Strong SCHEMBL2163079 0.76 KIF11 (0.46) LTA4HTSHRCCR6KCNH2KIF11
SCHEMBL9326176 0.76 LTA4H (0.43) LTA4HTSHRALDH1A1CA4KCNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 241 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0543950-B1 FLUORINATED QUINOLINE POLYMERS AND THE CORRESPONDING FLUORINATED MONOMERS HITACHI CHEMICAL CO LTD (JP) 1998-06-24 EP claimed
EP-0543950-A4 FLUORINATED QUINOLINE POLYMERS AND THE CORRESPONDING FLUORINATED MONOMERS 1993-10-27 EP claimed
EP-0543950-A1 FLUORINATED QUINOLINE POLYMERS AND THE CORRESPONDING FLUORINATED MONOMERS HITACHI CHEMICAL CO., LTD. (JP) 1993-06-02 EP claimed
EP-4097180-A1 HYDROPHOBIC COATING COMPOSITIONS Momentive Performance Materials Inc. (US) 2022-12-07 EP disclosed
EP-3902861-A1 CURABLE SILICONE-BASED COMPOSITIONS AND APPLICATIONS THEREOF Momentive Performance Materials Inc. (US) 2021-11-03 EP disclosed
WO-2021154504-A1 HYDROPHOBIC COATING COMPOSITIONS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2021-08-05 WO disclosed
EP-3794056-A1 ZWITTERION-FUNCTIONALIZED MULTICOMPONENT COPOLYMERS AND ASSOCIATED POLYMER BLENDS AND MEMBRANES Cytiva Sweden AB (SE) 2021-03-24 EP disclosed
WO-2020139642-A1 CURABLE SILICONE-BASED COMPOSITIONS AND APPLICATIONS THEREOF MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2020-07-02 WO disclosed
EP-3320542-A1 INSULATED WINDINGS AND METHODS OF MAKING THEREOF General Electric Company (US) 2018-05-16 EP disclosed
WO-2017176966-A1 SELF-COOLING ELECTRIC SUBMERSIBLE PUMP GENERAL ELECTRIC COMPANY (US) 2017-10-12 WO disclosed
EP-3221036-A1 ZWITTERION-FUNCTIONALIZED COPOLYMER HOLLOW-FIBER MEMBRANES AND ASSOCIATED METHOD General Electric Company (US) 2017-09-27 EP disclosed
US-20060074202-A1 Stabilized polycarbonate polyester composition GENERAL ELECTRIC COMPANY 2006-04-06 US disclosed
US-20060074155-A1 Halogen-free flame retardant polyester GENERAL ELECTRIC COMPANY 2006-04-06 US disclosed
US-20060069236-A1 Polyethersulfone compositions with high heat and good impact resistance GENERAL ELECTRIC COMPANY 2006-03-30 US disclosed
US-20060069222-A1 Curable formulations, cured compositions, and articles derived thereform GENERAL ELECTRIC COMPANY 2006-03-30 US disclosed
US-20060066004-A1 Method for controlling haze in an article comprising a polymer composition GENERAL ELECTRIC COMPANY 2006-03-30 US disclosed
US-20060069291-A1 Phosphazenium salt phase transfer catalysts GENERAL ELECTRIC COMPANY 2006-03-30 US disclosed
EP-1640403-A2 Polyethersulfone compositions with high heat and good impact resistance GENERAL ELECTRIC COMPANY (US) 2006-03-29 EP disclosed
EP-1640067-A2 Phosphazenium salt phase transfer catalysts GENERAL ELECTRIC COMPANY (US) 2006-03-29 EP disclosed
WO-2005073271-A1 COMPOSITIONS USEFUL AS COATINGS, THEIR PREPARATION, AND ARTICLES MADE THEREFROM GENERAL ELECTRIC COMPANY (US) 2005-08-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060069291-A1 Phosphazenium salt phase transfer catalysts PHOSPHO1, MPST, PAPSS1 LTA4H 3728/4885TSHR 3940/4885ALDH1A1 4713/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.