Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | SCN4A | P35499 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | VDR | P11473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4968551 | 0.86 | ALDH1A1 (0.41) | GABRA1GABRB1MEN1LMNAKMT2A | |
| SCHEMBL4967541 | 0.83 | ATM (0.34) | GABRA1GABRB1SCN4AATMMEN1 | |
| SCHEMBL4969111 | 0.83 | ATM (0.34) | GABRA1GABRB1SCN4AATMMEN1 | |
| SCHEMBL4969593 | 0.79 | NPC1 (0.32) | MEN1LMNAKMT2ASMN1; SMN2HTT | |
| SCHEMBL14113095 | 0.76 | TSHR (0.47) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL24446031 | 0.72 | RAPGEF4 (0.39) | GABRA1GABRB1MEN1KMT2A | |
| SCHEMBL4967999 | 0.71 | TRPM4 (0.40) | MEN1LMNAKMT2A | |
| SCHEMBL4968008 | 0.71 | TRPM4 (0.40) | MEN1LMNAKMT2A | |
| SCHEMBL4971229 | 0.70 | GAA (0.35) | LMNAHTTVDR | |
| SCHEMBL4969102 | 0.70 | GAA (0.35) | LMNAHTTVDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1985297-A1 | CARBOXYLIC ACID COMPOUND AND USE THEREOF | Japan Tobacco, Inc. (JP) | 2008-10-29 | — | — | EP | disclosed |
| US-20070197512-A1 | Carboxylic Acid Compounds and Use Thereof | JAPAN TOBACCO INC. (JP) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197512-A1 | Carboxylic Acid Compounds and Use Thereof | GLS, SLC10A1, SOAT1 | GABRA1 3227/4885GABRB1 3389/4885SCN4A 4080/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.