Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL496883 | 1.00 | JAK2 (0.33) | JAK2SYKADRA2ADNM1 | |
| SCHEMBL496921 | 0.84 | — | — | |
| SCHEMBL15062878 | 0.84 | — | — | |
| SCHEMBL12997207 | 0.84 | — | — | |
| SCHEMBL12997236 | 0.83 | NQO1 (0.32) | — | |
| SCHEMBL13811394 | 0.81 | — | — | |
| SCHEMBL496950 | 0.81 | DNM1 (0.51) | JAK2DNM1 | |
| SCHEMBL10024646 | 0.81 | DNM1 (0.51) | JAK2DNM1 | |
| SCHEMBL496948 | 0.81 | DNM1 (0.51) | JAK2DNM1 | |
| SCHEMBL10024649 | 0.81 | DNM1 (0.36) | JAK2DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2231607-B1 | AZOMETHINE DIRECT DYES OR REDUCED PRECURSORS OF THESE DYES OBTAINED FROM 2-AMINO-3-HYDROXYPYRIDINE, AND HAIR DYEING PROCESS USING THESE DYES AND PRECURSORS | OREAL (FR) | 2013-07-03 | — | — | EP | claimed |
| US-20110041262-A1 | AZOMETHINE DIRECT DYES OR REDUCED PRECURSORS OF AZOMETHINE DIRECT DYES OBTAINED FROM 2-ALKYLRESORCINOLS, AND HAIR DYEING PROCESS USING THESE DYES OR PRECURSORS | L'OREAL S.A (FR) | 2011-02-24 | — | — | US | claimed |
| US-20130167307-A1 | COMPOSITION COMPRISING AT LEAST ONE 2-PYRROLIDONE FUNCTIONALIZED IN THE 4 POSITION WITH A CARBOXYLIC ACID OR AMIDE, AND AT LEAST ONE DIRECT DYE OR A PIGMENT FOR DYEING KERATIN FIBRES | L'OREAL (FR) | 2013-07-04 | — | — | US | disclosed |
| EP-2231607-B1 | AZOMETHINE DIRECT DYES OR REDUCED PRECURSORS OF THESE DYES OBTAINED FROM 2-AMINO-3-HYDROXYPYRIDINE, AND HAIR DYEING PROCESS USING THESE DYES AND PRECURSORS | OREAL (FR) | 2013-07-03 | — | — | EP | disclosed |
| EP-2231607-B1 | AZOMETHINE DIRECT DYES OR REDUCED PRECURSORS OF THESE DYES OBTAINED FROM 2-AMINO-3-HYDROXYPYRIDINE, AND HAIR DYEING PROCESS USING THESE DYES AND PRECURSORS | OREAL (FR) | 2013-07-03 | — | — | EP | disclosed |
| US-8105394-B2 | Azomethine direct dyes or reduced precursors of azomethine direct dyes obtained from 2-alkylresorcinols, and hair dyeing process using these dyes or precursors | L'OREAL S.A. (FR) | 2012-01-31 | — | — | US | disclosed |
| US-8105394-B2 | Azomethine direct dyes or reduced precursors of azomethine direct dyes obtained from 2-alkylresorcinols, and hair dyeing process using these dyes or precursors | L'OREAL S.A. (FR) | 2012-01-31 | — | — | US | disclosed |
| US-8105394-B2 | Azomethine direct dyes or reduced precursors of azomethine direct dyes obtained from 2-alkylresorcinols, and hair dyeing process using these dyes or precursors | L'OREAL S.A. (FR) | 2012-01-31 | — | — | US | disclosed |
| US-20110041262-A1 | AZOMETHINE DIRECT DYES OR REDUCED PRECURSORS OF AZOMETHINE DIRECT DYES OBTAINED FROM 2-ALKYLRESORCINOLS, AND HAIR DYEING PROCESS USING THESE DYES OR PRECURSORS | L'OREAL S.A (FR) | 2011-02-24 | — | — | US | disclosed |
| US-20110041262-A1 | AZOMETHINE DIRECT DYES OR REDUCED PRECURSORS OF AZOMETHINE DIRECT DYES OBTAINED FROM 2-ALKYLRESORCINOLS, AND HAIR DYEING PROCESS USING THESE DYES OR PRECURSORS | L'OREAL S.A (FR) | 2011-02-24 | — | — | US | disclosed |
| US-20110041262-A1 | AZOMETHINE DIRECT DYES OR REDUCED PRECURSORS OF AZOMETHINE DIRECT DYES OBTAINED FROM 2-ALKYLRESORCINOLS, AND HAIR DYEING PROCESS USING THESE DYES OR PRECURSORS | L'OREAL S.A (FR) | 2011-02-24 | — | — | US | disclosed |
| WO-2009077392-A1 | AZOMETHINE DIRECT DYES OR REDUCED PRECURSORS OF THESE DYES OBTAINED FROM 2-AMINO-3-HYDROXYPYRIDINE, AND HAIR DYEING PROCESS USING THESE DYES AND PRECURSORS | L'OREAL (FR) | 2009-06-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130167307-A1 | COMPOSITION COMPRISING AT LEAST ONE 2-PYRROLIDONE FUNCTIONALIZED IN THE 4 POSITION WITH A CARBOXYLIC ACID OR AMIDE, AND AT LEAST ONE DIRECT DYE OR A PIGMENT FOR DYEING KERATIN FIBRES | KRT18, ADH1A, ADH1C | JAK2 4202/4885SYK 4278/4885ADRA2A 3097/4885 |
| US-20110041262-A1 | AZOMETHINE DIRECT DYES OR REDUCED PRECURSORS OF AZOMETHINE DIRECT DYES OBTAINED FROM 2-ALKYLRESORCINOLS, AND HAIR DYEING PROCESS USING THESE DYES OR PRECURSORS | KRT18, AKR1C4, QDPR | JAK2 4640/4885SYK 3274/4885ADRA2A 790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.