Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NOS3 | P29474 | 2/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.44 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.41 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31060546 | 0.81 | ALDH1A1 (0.74) | TAAR1ALDH1A1KDM4EMAPTMEN1 | |
| SCHEMBL5888383 | 0.81 | ALDH1A1 (0.74) | TAAR1ALDH1A1KDM4EMAPTMEN1 | |
| SCHEMBL5888381 | 0.74 | RAB9A (0.45) | TAAR1ALDH1A1MAPTMEN1LMNA | |
| SCHEMBL1880290 | 0.74 | KDM4E (0.51) | TAAR1KDM4EGPR84MAPTMEN1 | |
| SCHEMBL4575818 | 0.74 | LTC4S (0.67) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL21910343 | 0.73 | NPC1 (0.40) | ALDH1A1KDM4ECCNT1MAPTMEN1 | |
| SCHEMBL16037094 | 0.72 | TAAR1 (0.49) | TAAR1NOS3GPR84MAPTRPS6KB1 | |
| SCHEMBL12640326 | 0.71 | NPC1 (0.50) | ALDH1A1KDM4ECCNT1MAPTMEN1 | |
| SCHEMBL1060501 | 0.71 | ALDH1A1 (0.54) | ALDH1A1KDM4EMAPTMEN1LMNA | |
| SCHEMBL3906108 | 0.71 | L3MBTL1 (0.66) | TAAR1ALDH1A1KDM4ENOS3GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008016643-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-02-07 | — | — | WO | disclosed |