Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.33 |
| ▸ | P2RX2 | Q9UBL9 | 4/20 | 0.33 |
| ▸ | C5 | P01031 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5712240 | 0.81 | HTR2A (0.39) | HTR1AHTR2AHTR2CHTR2BCYP1A2 | |
| Hydrochloric Acid SCHEMBL3124253 | 0.79 | LMNA (0.38) | LMNAFDPSALOX5TLR8TRPV1 | |
| Hydrochloric Acid SCHEMBL3124250 | 0.79 | LMNA (0.38) | LMNAFDPSALOX5TLR8TRPV1 | |
| SCHEMBL31484735 | 0.79 | RARB (0.37) | HTR1AHTR2AHTR2CHTR2BCYP1A2 | |
| SCHEMBL14245331 | 0.78 | LMNA (0.43) | LMNAXDHFDPSALOX5TLR8 | |
| SCHEMBL1956731 | 0.78 | LMNA (0.43) | HTR2ACYP1A2CYP2D6LMNAXDH | |
| SCHEMBL1204813 | 0.77 | PDE4A (0.40) | HTR2ALMNAFDPSALOX5TRPV1 | |
| SCHEMBL1203769 | 0.77 | ALDH1A1 (0.49) | CYP3A4TSHRLMNAFDPSALOX5 | |
| SCHEMBL4581149 | 0.77 | TRPV1 (0.37) | CYP3A4TSHRLMNAFDPSALOX5 | |
| SCHEMBL1203776 | 0.77 | HTR2A (0.38) | HTR2ALMNAFDPSALOX5TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080269461-A1 | Polymeric Carbazole Compounds | KONINKLIJKE PHILIPS ELECTRONICS, N.V. (NL) | 2008-10-30 | — | — | US | disclosed |
| EP-1966270-A1 | POLYMERIC CARBAZOLE COMPOUNDS | Koninklijke Philips Electronics N.V. (NL) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007072240-A1 | POLYMERIC CARBAZOLE COMPOUNDS | KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) | 2007-06-28 | — | — | WO | disclosed |