Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | BCL9 | O00512 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4969715 | 0.84 | MEN1 (0.43) | MEN1KMT2ASMN1; SMN2L3MBTL1ACHE | |
| SCHEMBL3601068 | 0.78 | L3MBTL1 (0.40) | MEN1KMT2ASMN1; SMN2L3MBTL1GAA | |
| SCHEMBL3601072 | 0.78 | L3MBTL1 (0.40) | MEN1KMT2ASMN1; SMN2L3MBTL1GAA | |
| SCHEMBL4969726 | 0.74 | MGLL (0.38) | MEN1KMT2ASMN1; SMN2L3MBTL1GAA | |
| SCHEMBL3604530 | 0.68 | L3MBTL1 (0.40) | MEN1KMT2ASMN1; SMN2L3MBTL1ACHE | |
| SCHEMBL3604532 | 0.68 | L3MBTL1 (0.40) | MEN1KMT2ASMN1; SMN2L3MBTL1ACHE | |
| SCHEMBL23462473 | 0.68 | MEN1 (0.67) | MEN1KMT2ASMN1; SMN2ACHEGAA | |
| SCHEMBL1161760 | 0.68 | HTR2A (0.54) | KMT2ASMN1; SMN2L3MBTL1GAABCL9 | |
| SCHEMBL24439606 | 0.67 | MEN1 (0.65) | MEN1KMT2ASMN1; SMN2ACHESLC6A4 | |
| SCHEMBL12920133 | 0.66 | L3MBTL1 (0.39) | MEN1KMT2ASMN1; SMN2L3MBTL1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966139-A1 | ASPARTIC PROTEASE INHIBITORS | Vitae Pharmaceuticals, Inc. (US) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007070201-A1 | ASPARTIC PROTEASE INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2007-06-21 | — | — | WO | disclosed |