Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 2/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | BCL9 | O00512 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.35 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3601068 | 1.00 | L3MBTL1 (0.40) | L3MBTL1MGLLNAAAALDH1A1SMN1; SMN2 | |
| SCHEMBL3604530 | 0.83 | L3MBTL1 (0.40) | L3MBTL1MGLLNAAAALDH1A1SMN1; SMN2 | |
| SCHEMBL3604532 | 0.83 | L3MBTL1 (0.40) | L3MBTL1MGLLNAAAALDH1A1SMN1; SMN2 | |
| SCHEMBL4969726 | 0.79 | MGLL (0.38) | L3MBTL1MGLLNAAAALDH1A1SMN1; SMN2 | |
| SCHEMBL12920133 | 0.79 | L3MBTL1 (0.39) | L3MBTL1MGLLNAAAALDH1A1SMN1; SMN2 | |
| SCHEMBL5511617 | 0.78 | MGLL (0.53) | L3MBTL1MGLLNAAAALDH1A1SMN1; SMN2 | |
| SCHEMBL4969719 | 0.78 | MEN1 (0.39) | L3MBTL1MGLLALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL13256223 | 0.77 | MGLL (0.49) | L3MBTL1MGLLNAAAALDH1A1SMN1; SMN2 | |
| SCHEMBL5505931 | 0.76 | MGLL (0.46) | L3MBTL1MGLLNAAAALDH1A1SMN1; SMN2 | |
| SCHEMBL13503017 | 0.76 | KMT2A (0.44) | L3MBTL1MGLLNAAAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8487108-B2 | Piperidinyl carbamate intermediates for the synthesis of aspartic protease inhibitors | VITAE PHARMACEUTICALS, INC. (US) | 2013-07-16 | — | — | US | disclosed |
| EP-1966139-B1 | ASPARTIC PROTEASE INHIBITORS | VITAE PHARMACEUTICALS INC (US) | 2011-12-21 | — | — | EP | disclosed |
| US-20100048636-A1 | Aspartic Protease Inhibitors | VITAE PHARMACEUTICALS, INC. | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048636-A1 | Aspartic Protease Inhibitors | DNPEP, PEPD, SERPINB1 | L3MBTL1 3699/4885MGLL 1252/4885NAAA 191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.