Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.38 |
| ▸ | BCL9 | O00512 | 1/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3601068 | 0.79 | L3MBTL1 (0.40) | MGLLEPHX1BCL9CTNNB1L3MBTL1 | |
| SCHEMBL3601072 | 0.79 | L3MBTL1 (0.40) | MGLLEPHX1BCL9CTNNB1L3MBTL1 | |
| SCHEMBL4971092 | 0.76 | PPARG (0.41) | MGLLEPHX1L3MBTL1HTR2AALDH1A1 | |
| SCHEMBL4969719 | 0.74 | MEN1 (0.39) | MGLLBCL9CTNNB1L3MBTL1ALDH1A1 | |
| SCHEMBL12920133 | 0.73 | L3MBTL1 (0.39) | MGLLEPHX1L3MBTL1FAAHALDH1A1 | |
| SCHEMBL3604530 | 0.72 | L3MBTL1 (0.40) | MGLLEPHX1L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL3604532 | 0.72 | L3MBTL1 (0.40) | MGLLEPHX1L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL1161760 | 0.68 | HTR2A (0.54) | MGLLBCL9CTNNB1L3MBTL1HTR2A | |
| SCHEMBL7257343 | 0.68 | MGLL (0.57) | MGLLBCL9CTNNB1HTR2AALDH1A1 | |
| SCHEMBL6820152 | 0.68 | HTR2A (0.51) | MGLLEPHX1BCL9CTNNB1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966139-A1 | ASPARTIC PROTEASE INHIBITORS | Vitae Pharmaceuticals, Inc. (US) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007070201-A1 | ASPARTIC PROTEASE INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2007-06-21 | — | — | WO | disclosed |