Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | APLNR | P35414 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3831696 | 0.82 | MAPT (0.48) | LMNAHPGDCTSKALDH1A1 | |
| SCHEMBL3843320 | 0.78 | EPHX2 (0.39) | — | |
| SCHEMBL4971081 | 0.77 | MMP13 (0.43) | HPGDALDH1A1 | |
| SCHEMBL4966953 | 0.76 | EPHX2 (0.44) | — | |
| SCHEMBL4969822 | 0.76 | CTSS (0.39) | F2SLC1A3SLC1A2SLC1A1LMNA | |
| SCHEMBL18415486 | 0.73 | GRM5 (0.53) | LMNATHRBHPGDKDM4CGRM5 | |
| SCHEMBL2852749 | 0.73 | HPGD (0.43) | SLC1A3SLC1A2SLC1A1LMNATHRB | |
| SCHEMBL12265800 | 0.72 | HDAC6 (0.51) | F2LMNATHRBHPGDKDM4C | |
| SCHEMBL2852748 | 0.72 | GRM5 (0.40) | SLC1A3SLC1A2SLC1A1LMNATHRB | |
| SCHEMBL27723274 | 0.71 | CTSS (0.39) | SLC1A3SLC1A2SLC1A1LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1963277-A1 | FLUORINATED COMPOUNDS | NPS PHARMACEUTICALS, INC. (US) | 2008-09-03 | — | — | EP | claimed |
| WO-2007076306-A1 | FLUORINATED COMPOUNDS | NPS PHARMACEUTICALS, INC. (US) | 2007-07-05 | — | — | WO | claimed |