Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | HPGD | P15428 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.54 |
| ▸ | CBFB | Q13951 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.50 |
| ▸ | STAMBP | O95630 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4969813 | 0.79 | ALDH1A1 (0.64) | ALDH1A1HPGDLMNAHTTKDM4E | |
| SCHEMBL31522183 | 0.79 | PIM1 (0.52) | ALDH1A1HPGDLMNAPOLBMEN1 | |
| SCHEMBL27961959 | 0.77 | PLK1 (0.65) | POLBHDAC2 | |
| SCHEMBL31522168 | 0.76 | PREP (0.49) | ALDH1A1HPGDLMNAPOLBKMT2A | |
| SCHEMBL9202857 | 0.76 | HPGD (0.71) | ALDH1A1HPGDLMNAHTTKDM4E | |
| SCHEMBL11829949 | 0.76 | LMNA (0.72) | ALDH1A1HPGDLMNAHTTKDM4E | |
| SCHEMBL5318951 | 0.75 | CNR1 (0.67) | ALDH1A1HPGDLMNAHTTKDM4E | |
| SCHEMBL4907748 | 0.75 | SORT1 (0.58) | ALDH1A1HPGDLMNAHTTKDM4E | |
| SCHEMBL6093501 | 0.74 | HPGD (0.69) | ALDH1A1HPGDLMNAHTTKDM4E | |
| SCHEMBL7220820 | 0.74 | HPGD (0.69) | ALDH1A1HPGDLMNAHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1973888-A1 | ISOXAZOLINES FOR CONTROLLING INVERTEBRATE PESTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-10-01 | — | — | EP | disclosed |
| WO-2007079162-A1 | ISOXAZOLINES FOR CONTROLLING INVERTEBRATE PESTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-07-12 | — | — | WO | disclosed |