Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | HPGD | P15428 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.55 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.54 |
| ▸ | STAMBP | O95630 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.52 |
| ▸ | CBFB | Q13951 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2203862 | 0.86 | EGLN1 (0.74) | ALDH1A1HPGDLMNAHTTRAB9A | |
| SCHEMBL6983554 | 0.84 | EGLN1 (0.76) | HPGDLMNARAB9ANPC1MEN1 | |
| SCHEMBL7220820 | 0.81 | HPGD (0.69) | ALDH1A1HPGDLMNAHTTRAB9A | |
| SCHEMBL6382378 | 0.81 | HPGD (0.69) | ALDH1A1HPGDLMNAHTTRAB9A | |
| SCHEMBL9202857 | 0.80 | HPGD (0.71) | ALDH1A1HPGDLMNAHTTRAB9A | |
| SCHEMBL11829949 | 0.80 | LMNA (0.72) | ALDH1A1HPGDLMNAHTTRAB9A | |
| SCHEMBL4969859 | 0.79 | ALDH1A1 (0.59) | ALDH1A1HPGDLMNAHTTRAB9A | |
| SCHEMBL2713994 | 0.79 | NPC1 (0.47) | ALDH1A1HPGDLMNAHTTRAB9A | |
| SCHEMBL28239389 | 0.78 | EGLN1 (0.60) | HPGDRAB9ANPC1KDM4EMEN1 | |
| SCHEMBL7382937 | 0.78 | EGLN1 (0.74) | ALDH1A1HPGDLMNARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1973888-A1 | ISOXAZOLINES FOR CONTROLLING INVERTEBRATE PESTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-10-01 | — | — | EP | claimed |
| WO-2007079162-A1 | ISOXAZOLINES FOR CONTROLLING INVERTEBRATE PESTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-07-12 | — | — | WO | claimed |