Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4969784 | 0.95 | KDM4E (0.52) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL7597791 | 0.93 | KDM4E (0.50) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL3863603 | 0.89 | CA1 (0.43) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL3540841 | 0.85 | ALDH1A1 (0.52) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL2453322 | 0.84 | ALDH1A1 (0.50) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL6283344 | 0.84 | CA2 (0.53) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL6284410 | 0.84 | ALDH1A1 (0.50) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL6279711 | 0.82 | CA2 (0.54) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL1334286 | 0.82 | ALDH1A1 (0.48) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL408714 | 0.82 | TSHR (0.48) | KDM4EUSP2ALDH1A1LMNAMMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008106204-A1 | MACROLIDE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | RIB-X-PHARMACEUTICALS, INC. (US) | 2008-09-04 | — | — | WO | disclosed |