SCHEMBL4969784

SCHEMBL4969784

CS(=O)(=O)OCCCCc1ccc(I)cc1

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.52
USP2 O75604 1/20 0.52
ALDH1A1 P00352 1/20 0.52
LMNA P02545 1/20 0.52
MMP9 P14780 1/20 0.52
ALOX15 P16050 1/20 0.52
TSHR P16473 1/20 0.52
CA2 P00918 3/20 0.38
SMN1; SMN2 Q16637 1/20 0.35
SIGMAR1 Q99720 2/20 0.35
MITF O75030 1/20 0.35
POLB P06746 1/20 0.34
HRH4 Q9H3N8 1/20 0.34
HRH3 Q9Y5N1 1/20 0.34
MGLL Q99685 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7597791 0.98 KDM4E (0.50) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL4970012 0.95 KDM4E (0.48) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL3863603 0.87 CA1 (0.43) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL26316551 0.84 ALDH1A1 (0.54) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL16825858 0.83 TSHR (0.52) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL11279959 0.83 TSHR (0.52) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL2658522 0.82 KDM4E (0.56) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL1843955 0.81 APLNR (0.51) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL4802236 0.81 LMNA (0.46) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL23014971 0.81 KDM4E (0.54) KDM4EUSP2ALDH1A1LMNAMMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2308910-B1 POLYMER COMPOUND AND LIGHT-EMITTING ELEMENT USING SAME SUMITOMO CHEMICAL CO (JP) 2017-03-01 EP disclosed
US-8993124-B2 Polymer compound comprising aryl repeating units with crosslinking pendent groups and light-emitting element using same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-03-31 US disclosed
US-8993124-B2 Polymer compound comprising aryl repeating units with crosslinking pendent groups and light-emitting element using same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-03-31 US disclosed
US-20110127516-A1 POLYMER COMPOUND AND LIGHT-EMITTING ELEMENT USING SAME SUMITOMO CHEMICAL COMPANY ,LIMITED (JP) 2011-06-02 US disclosed
WO-2008106204-A1 MACROLIDE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME RIB-X-PHARMACEUTICALS, INC. (US) 2008-09-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110127516-A1 POLYMER COMPOUND AND LIGHT-EMITTING ELEMENT USING SAME RER1, NAP1L1, CRY1 KDM4E 1822/4885USP2 3848/4885ALDH1A1 730/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.