SCHEMBL4970013

SCHEMBL4970013

Cc1cc(C)c2c(c1)N(CCC=O)C(=O)C(c1ccccc1)O2

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
F10 P00742 9/20 0.39
SLC5A2 P31639 3/20 0.38
RXFP1 Q9HBX9 1/20 0.35
RAB9A P51151 1/20 0.34
CA2 P00918 1/20 0.33
REN P00797 1/20 0.33
PRSS1 P07477 5/20 0.33
SLC5A1 P13866 2/20 0.33
PLG P00747 2/20 0.32
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
KMT2A Q03164 1/20 0.32
F2 P00734 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4969922 0.86 F10 (0.43) F10RAB9APRSS1PLGKMT2A
SCHEMBL4973963 0.84 RXFP1 (0.41) F10SLC5A2RXFP1RAB9APRSS1
SCHEMBL4970062 0.84 F10 (0.45) F10RXFP1RENPRSS1ALDH1A1
SCHEMBL4970028 0.81 F10 (0.47) F10RXFP1RENPRSS1PLG
SCHEMBL4969051 0.78 F10 (0.42) F10RENPRSS1PLGKMT2A
SCHEMBL4970579 0.77 F10 (0.40) F10RENPRSS1PLGKMT2A
SCHEMBL4969372 0.76 F10 (0.41) F10PRSS1PLGKMT2AF2
SCHEMBL4969045 0.76 F10 (0.41) F10PRSS1PLGKMT2AF2
SCHEMBL4970877 0.74 F10 (0.44) F10RAB9ARENPRSS1PLG
SCHEMBL4969888 0.74 F10 (0.46) F10RAB9APRSS1PLGKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1985297-A1 CARBOXYLIC ACID COMPOUND AND USE THEREOF Japan Tobacco, Inc. (JP) 2008-10-29 EP disclosed
US-20070197512-A1 Carboxylic Acid Compounds and Use Thereof JAPAN TOBACCO INC. (JP) 2007-08-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070197512-A1 Carboxylic Acid Compounds and Use Thereof GLS, SLC10A1, SOAT1 F10 4290/4885SLC5A2 23/4885RXFP1 1067/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.