SCHEMBL4969922

SCHEMBL4969922

Cc1cccc2c1OC(c1ccccc1)C(=O)N2CCC=O

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
F10 P00742 16/20 0.43
RAB9A P51151 1/20 0.39
PRSS1 P07477 11/20 0.36
KMT2A Q03164 1/20 0.36
F2 P00734 9/20 0.35
PLG P00747 6/20 0.35
HTT P42858 1/20 0.34
PROC P04070 1/20 0.34
HTR7 P34969 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4969051 0.87 F10 (0.42) F10PRSS1KMT2AF2PLG
SCHEMBL4970013 0.86 F10 (0.39) F10RAB9APRSS1KMT2AF2
SCHEMBL4970579 0.86 F10 (0.40) F10PRSS1KMT2AF2PLG
SCHEMBL4969045 0.85 F10 (0.41) F10PRSS1KMT2AF2PLG
SCHEMBL4969372 0.85 F10 (0.41) F10PRSS1KMT2AF2PLG
SCHEMBL4971439 0.83 RAB9A (0.45) F10RAB9APRSS1KMT2AF2
SCHEMBL7125248 0.79 F10 (0.58) F10PRSS1F2PLGPROC
SCHEMBL4970062 0.79 F10 (0.45) F10PRSS1KMT2A
SCHEMBL4970028 0.78 F10 (0.47) F10PRSS1KMT2AF2PLG
SCHEMBL4970877 0.74 F10 (0.44) F10RAB9APRSS1KMT2AF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1985297-A1 CARBOXYLIC ACID COMPOUND AND USE THEREOF Japan Tobacco, Inc. (JP) 2008-10-29 EP disclosed
US-20070197512-A1 Carboxylic Acid Compounds and Use Thereof JAPAN TOBACCO INC. (JP) 2007-08-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070197512-A1 Carboxylic Acid Compounds and Use Thereof GLS, SLC10A1, SOAT1 F10 4290/4885RAB9A 3322/4885PRSS1 440/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.