Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 12/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.39 |
| ▸ | PLG | P00747 | 4/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | REN | P00797 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
| ▸ | PROC | P04070 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4970062 | 0.92 | F10 (0.45) | F10RXFP1PRSS1KMT2AREN | |
| SCHEMBL4969888 | 0.86 | F10 (0.46) | F10PRSS1PLGGSK3BF2 | |
| SCHEMBL16092754 | 0.84 | F10 (0.46) | F10RXFP1MAOBGSK3BKMT2A | |
| SCHEMBL4970643 | 0.84 | RXFP1 (0.48) | F10RXFP1PRSS1PLGF2 | |
| SCHEMBL4970013 | 0.81 | F10 (0.39) | F10RXFP1PRSS1PLGF2 | |
| SCHEMBL4970877 | 0.80 | F10 (0.44) | F10PRSS1PLGGSK3BF2 | |
| SCHEMBL7115767 | 0.78 | F10 (0.61) | F10PRSS1PLGF2KMT2A | |
| SCHEMBL4969922 | 0.78 | F10 (0.43) | F10PRSS1PLGF2KMT2A | |
| SCHEMBL4973316 | 0.75 | ALDH1A1 (0.52) | F10RXFP1KMT2AREN | |
| SCHEMBL4969051 | 0.74 | F10 (0.42) | F10PRSS1PLGF2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1985297-A1 | CARBOXYLIC ACID COMPOUND AND USE THEREOF | Japan Tobacco, Inc. (JP) | 2008-10-29 | — | — | EP | disclosed |
| US-20070197512-A1 | Carboxylic Acid Compounds and Use Thereof | JAPAN TOBACCO INC. (JP) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197512-A1 | Carboxylic Acid Compounds and Use Thereof | GLS, SLC10A1, SOAT1 | F10 4290/4885RXFP1 1067/4885PRSS1 440/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.