Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TARBP2 | Q15633 | 6/20 | 0.40 |
| ▸ | PDCD4 | Q53EL6 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4958502 | 0.82 | ALDH1A1 (0.44) | TARBP2PDCD4ALDH1A1CYP1A2GAA | |
| SCHEMBL4985307 | 0.75 | TARBP2 (0.41) | TARBP2PDCD4ALDH1A1CYP1A2GAA | |
| SCHEMBL29110021 | 0.69 | KMT2A (0.40) | ALDH1A1CYP1A2GAAKDM4EHPGD | |
| SCHEMBL4961136 | 0.67 | ALDH1A1 (0.47) | TARBP2PDCD4ALDH1A1CYP1A2GAA | |
| SCHEMBL3821339 | 0.67 | TARBP2 (0.49) | TARBP2PDCD4ALDH1A1CYP1A2GAA | |
| Hydrochloric Acid SCHEMBL11140661 | 0.66 | ALDH1A1 (0.46) | TARBP2PDCD4ALDH1A1CYP1A2GAA | |
| SCHEMBL2616840 | 0.65 | TARBP2 (0.58) | TARBP2PDCD4ALDH1A1CYP1A2KDM4E | |
| SCHEMBL21572852 | 0.65 | ALDH1A1 (0.56) | TARBP2ALDH1A1CYP1A2GAAKDM4E | |
| SCHEMBL9869213 | 0.64 | CA12 (0.46) | TARBP2PDCD4ALDH1A1CYP1A2GAA | |
| SCHEMBL3641559 | 0.64 | FBP1 (0.53) | TARBP2PDCD4ALDH1A1CYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966176-A1 | HETEROCYCLIC GABA-B MODULATORS | AstraZeneca AB (SE) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007073296-A1 | HETEROCYCLIC GABA-B MODULATORS | ASTRAZENECA AB (SE) | 2007-06-28 | — | — | WO | disclosed |