Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4973173 | 0.91 | LMNA (0.40) | HTR1ASLC6A2HTR2CHTR2BSIGMAR1 | |
| SCHEMBL4969761 | 0.90 | GAA (0.48) | HTR1ASLC6A2HTR2CHTR2BSIGMAR1 | |
| SCHEMBL4972701 | 0.88 | MAOB (0.40) | GAAALDH1A1MAOBKCNA5LMNA | |
| SCHEMBL3603597 | 0.88 | MAPT (0.33) | HTR1ASLC6A2HTR2CHTR2BSIGMAR1 | |
| SCHEMBL4972270 | 0.83 | KCNE1 (0.38) | HTR2BESR2ALDH1A1MAOBLMNA | |
| SCHEMBL2473650 | 0.77 | HTR7 (0.35) | HTR2BSIGMAR1CNR1CNR2ALDH1A1 | |
| SCHEMBL15253596 | 0.77 | HTR2C (0.40) | HTR1ASLC6A2HTR2CHTR2BSIGMAR1 | |
| SCHEMBL5868353 | 0.72 | IDO1 (0.40) | HTR1ASLC6A2HTR2CHTR2BSIGMAR1 | |
| SCHEMBL5868357 | 0.72 | IDO1 (0.40) | HTR1ASLC6A2HTR2CHTR2BSIGMAR1 | |
| SCHEMBL6274078 | 0.72 | IDO1 (0.40) | HTR1ASLC6A2HTR2CHTR2BSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1408036-B1 | PROCESS FOR PRODUCING BENZOFURAN DERIVATIVE | TAKEDA PHARMACEUTICAL (JP) | 2008-08-27 | — | — | EP | disclosed |
| US-7323577-B2 | Process for producing benzofuran derivative | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-01-29 | — | — | US | disclosed |
| US-20060142598-A1 | Process for producing benzofuran derivative | TAWADA HIROYUKI | 2006-06-29 | — | — | US | disclosed |
| US-7034166-B2 | Process for producing benzofuran derivative | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-04-25 | — | — | US | disclosed |
| US-20040210066-A1 | Process for producing benzofuran derivative | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-10-21 | — | — | US | disclosed |
| EP-1408036-A1 | PROCESS FOR PRODUCING BENZOFURAN DERIVATIVE | Takeda Chemical Industries, Ltd. (JP) | 2004-04-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040210066-A1 | Process for producing benzofuran derivative | IWS1, HAT1, BRD1 | HTR1A 1944/4885SLC6A2 4391/4885HTR2C 1416/4885 |
| US-20060142598-A1 | Process for producing benzofuran derivative | AHR, CBR3, HAT1 | HTR1A 2179/4885SLC6A2 4260/4885HTR2C 1589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.