Sulfuric Acid

Sulfuric Acid

SCHEMBL4970729

O=C1CC(O)C(=O)N1.O=S(=O)(O)O

nearest known ligand 0.43

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAP3K14 Q99558 1/20 0.43
CRBN Q96SW2 1/20 0.36
CYP19A1 P11511 1/20 0.33
MEN1 O00255 1/20 0.33
APEX1 P27695 1/20 0.33
KMT2A Q03164 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
IDO1 P14902 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1028532 0.91 MAP3K14 (0.40) MAP3K14CRBNCYP19A1MEN1APEX1
SCHEMBL15494454 0.91
SCHEMBL31244467 0.88
Hydrochloric Acid SCHEMBL3986242 0.88
Phosphine SCHEMBL22345181 0.88
Ammonia Solution, Strong SCHEMBL25176856 0.88
SCHEMBL320576 0.88
SCHEMBL114368 0.88 MAP3K14 (0.38) MAP3K14CRBNCYP19A1MEN1KMT2A
SCHEMBL114518 0.86 MAP3K14 (0.36) MAP3K14CRBN
Ethane SCHEMBL28857929 0.86 MAP3K14 (0.46) MAP3K14CRBNCYP19A1MEN1APEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115052868-A Cannabinoid sulfate, and salts and uses thereof 伦敦制药与研究公司 2022-09-13 CN claimed
EP-3215567-A1 METHOD OF PRODUCTION OF GRAFT CO-POLYMER EXCIPIENT WITH A SUPERIOR PEPTIDE AND PROTEIN BINDING PROPERTY Pharmain Corporation (US) 2017-09-13 EP claimed
WO-2016073518-A1 METHOD OF PRODUCTION OF GRAFT CO-POLYMER EXCIPIENT WITH A SUPERIOR PEPTIDE AND PROTEIN BINDING PROPERTY PHARMAIN CORPORATION (US) 2016-05-12 WO claimed
CN-115052868-A Cannabinoid sulfate, and salts and uses thereof 伦敦制药与研究公司 2022-09-13 CN disclosed
EP-1971372-A2 HYDROPHOBIC CORE CARRIER COMPOSITIONS FOR DELIVERY OF THERAPEUTIC AGENTS, METHODS OF MAKING AND USING THE SAME Pharmain, Ltd. (US) 2008-09-24 EP disclosed
WO-2007076371-A2 HYDROPHOBIC CORE CARRIER COMPOSITIONS FOR DELIVERY OF THERAPEUTIC AGENTS, METHODS OF MAKING AND USING THE SAME PHARMAIN CORPORATION (US) 2007-07-05 WO disclosed