Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4970993 | 1.00 | ALDH1A1 (0.64) | ALDH1A1NOTUMMAPTRXFP1LMNA | |
| SCHEMBL4969919 | 0.81 | NOTUM (0.61) | NOTUMMAPTRXFP1LMNATHRB | |
| SCHEMBL4969128 | 0.81 | NOTUM (0.61) | NOTUMMAPTRXFP1LMNATHRB | |
| SCHEMBL4969115 | 0.81 | NOTUM (0.61) | NOTUMMAPTRXFP1LMNATHRB | |
| SCHEMBL14433154 | 0.78 | ALDH1A1 (0.50) | ALDH1A1MAPTLMNA | |
| SCHEMBL4970676 | 0.76 | ALDH1A1 (0.49) | ALDH1A1MAPTLMNAHTT | |
| SCHEMBL12723657 | 0.76 | NOTUM (0.54) | ALDH1A1NOTUMMAPTRXFP1LMNA | |
| SCHEMBL4969256 | 0.76 | MAPT (0.59) | ALDH1A1NOTUMMAPTRXFP1LMNA | |
| SCHEMBL4970673 | 0.76 | ALDH1A1 (0.49) | ALDH1A1MAPTLMNAHTT | |
| SCHEMBL13525163 | 0.76 | NOTUM (0.69) | ALDH1A1NOTUMMAPTRXFP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1985297-A1 | CARBOXYLIC ACID COMPOUND AND USE THEREOF | Japan Tobacco, Inc. (JP) | 2008-10-29 | — | — | EP | disclosed |
| US-20070197512-A1 | Carboxylic Acid Compounds and Use Thereof | JAPAN TOBACCO INC. (JP) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197512-A1 | Carboxylic Acid Compounds and Use Thereof | GLS, SLC10A1, SOAT1 | ALDH1A1 142/4885NOTUM 593/4885MAPT 387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.