Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4970673 | 1.00 | ALDH1A1 (0.49) | ALDH1A1MAPTHTTLMNAL3MBTL1 | |
| SCHEMBL4969747 | 0.85 | MAPT (0.35) | ALDH1A1MAPTHTTL3MBTL1MEN1 | |
| SCHEMBL14433154 | 0.76 | ALDH1A1 (0.50) | ALDH1A1MAPTLMNAHCAR2 | |
| SCHEMBL4970993 | 0.76 | ALDH1A1 (0.64) | ALDH1A1MAPTHTTLMNA | |
| SCHEMBL4970985 | 0.76 | ALDH1A1 (0.64) | ALDH1A1MAPTHTTLMNA | |
| SCHEMBL23729551 | 0.67 | L3MBTL1 (0.37) | ALDH1A1MAPTLMNAL3MBTL1MEN1 | |
| SCHEMBL30697866 | 0.65 | ALDH1A1 (0.70) | ALDH1A1MAPTLMNAL3MBTL1MEN1 | |
| SCHEMBL2775391 | 0.64 | CA12 (0.51) | ALDH1A1MAPTLMNAHCAR2KDM4E | |
| SCHEMBL2775389 | 0.64 | CA12 (0.51) | ALDH1A1MAPTLMNAHCAR2KDM4E | |
| Diethyl Maleate SCHEMBL28963047 | 0.64 | HCAR2 (0.53) | ALDH1A1MAPTHTTLMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1985297-A1 | CARBOXYLIC ACID COMPOUND AND USE THEREOF | Japan Tobacco, Inc. (JP) | 2008-10-29 | — | — | EP | disclosed |
| US-20070197512-A1 | Carboxylic Acid Compounds and Use Thereof | JAPAN TOBACCO INC. (JP) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197512-A1 | Carboxylic Acid Compounds and Use Thereof | GLS, SLC10A1, SOAT1 | ALDH1A1 142/4885MAPT 387/4885HTT 772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.