SCHEMBL4972140

SCHEMBL4972140

O=C(O)CCN1C(=O)C(c2ccccc2)Oc2c(Br)cccc21

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.41
F10 P00742 7/20 0.40
MEN1 O00255 3/20 0.40
LMNA P02545 1/20 0.40
MME P08473 4/20 0.38
ACE P12821 4/20 0.38
PRSS1 P07477 4/20 0.38
TP53 P04637 1/20 0.38
MDM2 Q00987 1/20 0.38
F2 P00734 3/20 0.37
PLG P00747 1/20 0.37
RAB9A P51151 2/20 0.37
NPC1 O15118 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4971439 0.86 RAB9A (0.45) KMT2AF10MEN1LMNAMME
SCHEMBL4970407 0.85 F10 (0.42) KMT2AF10MEN1LMNAMME
SCHEMBL4970579 0.83 F10 (0.40) KMT2AF10PRSS1F2PLG
SCHEMBL4970137 0.83 F10 (0.41) KMT2AF10MEN1LMNAMME
SCHEMBL4969257 0.83 KMT2A (0.41) KMT2AF10MEN1LMNAMME
SCHEMBL4971594 0.80 MME (0.40) KMT2AMEN1LMNAMMEACE
SCHEMBL4973963 0.77 RXFP1 (0.41) KMT2AF10MEN1LMNAMME
SCHEMBL4972118 0.74 KMO (0.57) KMT2AF10LMNAPRSS1RAB9A
SCHEMBL4973316 0.74 ALDH1A1 (0.52) KMT2AF10MEN1LMNARAB9A
SCHEMBL4970643 0.73 RXFP1 (0.48) KMT2AF10MEN1LMNAMME

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1985297-A1 CARBOXYLIC ACID COMPOUND AND USE THEREOF Japan Tobacco, Inc. (JP) 2008-10-29 EP claimed
US-20070197512-A1 Carboxylic Acid Compounds and Use Thereof JAPAN TOBACCO INC. (JP) 2007-08-23 US claimed
EP-1985297-A1 CARBOXYLIC ACID COMPOUND AND USE THEREOF Japan Tobacco, Inc. (JP) 2008-10-29 EP disclosed
US-20070197512-A1 Carboxylic Acid Compounds and Use Thereof JAPAN TOBACCO INC. (JP) 2007-08-23 US disclosed
US-20070197512-A1 Carboxylic Acid Compounds and Use Thereof JAPAN TOBACCO INC. (JP) 2007-08-23 US disclosed
US-20070197512-A1 Carboxylic Acid Compounds and Use Thereof JAPAN TOBACCO INC. (JP) 2007-08-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070197512-A1 Carboxylic Acid Compounds and Use Thereof GLS, SLC10A1, SOAT1 KMT2A 1121/4885F10 4290/4885MEN1 4288/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.