Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4972027 | 0.92 | MAPT (0.46) | KDM4EALDH1A1LMNAGAAMAPT | |
| SCHEMBL4966957 | 0.88 | KDM4E (0.45) | KDM4EALDH1A1LMNAGAAMAPT | |
| SCHEMBL4968337 | 0.88 | MAPT (0.44) | KDM4EALDH1A1LMNAGAAMAPT | |
| SCHEMBL4972774 | 0.85 | MEN1 (0.41) | ALDH1A1LMNAMAPTTBXA2R | |
| SCHEMBL4970200 | 0.85 | MAPT (0.43) | KDM4EALDH1A1LMNAGAAMAPT | |
| SCHEMBL4971672 | 0.83 | HTR6 (0.43) | KDM4EALDH1A1LMNAGAAMAPT | |
| SCHEMBL4970261 | 0.80 | KDM4E (0.42) | KDM4EALDH1A1LMNAGAAMAPT | |
| SCHEMBL4969062 | 0.78 | KDM4E (0.43) | KDM4EALDH1A1LMNAGAAMAPT | |
| SCHEMBL13666164 | 0.77 | KCNH2 (0.41) | KDM4EALDH1A1LMNAGAAMAPT | |
| SCHEMBL4968907 | 0.75 | HTR6 (0.41) | ALDH1A1LMNAMAPTTBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1654228-B1 | TETRAHYDROCARBAZOLE DERIVATIVES AND THEIR PHARMACEUTICAL USE | SMITHKLINE BEECHAM CORP (US) | 2008-10-22 | — | — | EP | claimed |