Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30843775 | 0.76 | AADAT (0.46) | NOTUMMEN1KMT2A | |
| SCHEMBL1673259 | 0.76 | AADAT (0.46) | NOTUMMEN1KMT2A | |
| Bromide SCHEMBL30825763 | 0.75 | AADAT (0.44) | NOTUMMEN1KMT2A | |
| Bromide SCHEMBL5705627 | 0.75 | AADAT (0.44) | NOTUMMEN1KMT2A | |
| SCHEMBL1754235 | 0.68 | SMN1; SMN2 (0.58) | SMN1; SMN2SIGMAR1POLBNOTUMTSHR | |
| SCHEMBL23505301 | 0.68 | MTNR1A (0.49) | SMN1; SMN2POLBNOTUMTSHRALDH1A1 | |
| SCHEMBL9685608 | 0.68 | TSHR (0.41) | SMN1; SMN2SIGMAR1POLBTSHRALDH1A1 | |
| SCHEMBL9224567 | 0.67 | SIGMAR1 (0.52) | SMN1; SMN2SIGMAR1NOTUMTSHRMAPT | |
| SCHEMBL6226824 | 0.67 | SMN1; SMN2 (0.47) | SMN1; SMN2SIGMAR1POLBNOTUMTSHR | |
| Methane SCHEMBL10699702 | 0.67 | MTNR1A (0.48) | SMN1; SMN2POLBNOTUMTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008134071-A1 | MULTIMODAL ABUSE RESISTANT EXTENDED RELEASE FORMULATIONS | THERAQUEST BIOSCIENCES, INC. (US) | 2008-11-06 | — | — | WO | claimed |
| WO-2008134071-A1 | MULTIMODAL ABUSE RESISTANT EXTENDED RELEASE FORMULATIONS | THERAQUEST BIOSCIENCES, INC. (US) | 2008-11-06 | — | — | WO | disclosed |