SCHEMBL1673259

SCHEMBL1673259

OC1Cc2ccccc2N1O

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
AADAT Q8N5Z0 2/20 0.46
GOT1 P17174 1/20 0.46
KYAT1 Q16773 1/20 0.46
KYAT3 Q6YP21 1/20 0.46
NOTUM Q6P988 3/20 0.42
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
HTR2A P28223 5/20 0.36
HTR2C P28335 5/20 0.36
HTR2B P41595 4/20 0.36
ADRA2A P08913 1/20 0.36
ADRA2B P18089 1/20 0.36
ADRA2C P18825 1/20 0.36
SLC6A2 P23975 1/20 0.36
SLC6A4 P31645 1/20 0.36
ADRA1A P35348 1/20 0.36
HRH1 P35367 1/20 0.36
KCNH2 Q12809 1/20 0.36
ACE P12821 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30843775 1.00 AADAT (0.46) AADATGOT1KYAT1KYAT3NOTUM
Bromide SCHEMBL5705627 0.98 AADAT (0.44) AADATGOT1KYAT1KYAT3NOTUM
Bromide SCHEMBL30825763 0.98 AADAT (0.44) AADATGOT1KYAT1KYAT3NOTUM
SCHEMBL4866473 0.77 DRD2 (0.38) HTR2AHTR2CHTR2BADRA2C
SCHEMBL10417968 0.77 AADAT (0.44) AADATGOT1KYAT1KYAT3NOTUM
SCHEMBL3739629 0.77 AADAT (0.44) AADATGOT1KYAT1KYAT3NOTUM
SCHEMBL28070868 0.77 AADAT (0.53) AADATGOT1KYAT1KYAT3NOTUM
SCHEMBL12094610 0.77 NOTUM (0.44) AADATGOT1KYAT1KYAT3NOTUM
SCHEMBL4973164 0.76 SMN1; SMN2 (0.43) NOTUMMEN1KMT2A
SCHEMBL23445600 0.72 RNASEH1 (0.49) KMT2AHTR2AHTR2CHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 323 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144724-A1 Mixture of at least five surfactants (I1) to (I5) WELLA GERMANY GMBH (DE) 2026-05-28 US claimed
US-12636241-B1 Method and composition for oxidative hair coloring WELLA OPERATIONS US LLC (US) 2026-05-26 US claimed
WO-2026104266-A1 USE OF A NATURAL OCCURRING POLYPHENOL AS AN OXIDATIVE COUPLER DYE PRECURSOR IN AN OXIDATIVE HAIR COLOURING COMPOSITION WELLA GERMANY GMBH (DE) 2026-05-21 WO claimed
EP-4739272-A1 OXIDATIVE HAIR COLOURING COMPOSITION Wella Germany GmbH (DE) 2026-05-13 EP claimed
EP-4731170-A1 OXIDATIVE HAIR COLOURING COMPOSITION COMPRISING A CHELANT MIXTURE Wella Germany GmbH (DE) 2026-04-29 EP claimed
US-12564545-B2 Hair coloring compositions comprising 2-amino-1-propanol as alkalising agents WELLA GERMANY GMBH (DE) 2026-03-03 US claimed
EP-4552630-A1 RESORCINOL FREE PERMANENT HAIR COLOR COMPOSITION AND METHOD Wella Operations US, LLC (US) 2025-05-14 EP claimed
WO-2025031867-A1 OXIDATIVE HAIR COLOURING COMPOSITION COMPRISING A CHELANT MIXTURE WELLA GERMANY GMBH (DE) 2025-02-13 WO claimed
WO-2025008339-A1 OXIDATIVE HAIR COLOURING COMPOSITION WELLA GERMANY GMBH (DE) 2025-01-09 WO claimed
US-20240342067-A1 Hair Coloring Compositions Comprising 2-Amino-1-Propanol As Alkalising Agents WELLA GERMANY GMBH (DE) 2024-10-17 US claimed
EP-1342466-B1 Non-colouring composition containing a precursor and a catalyst for oxidative reaction OREAL (FR) 2007-10-17 EP claimed
WO-2004056331-A1 COMPOSITION FOR DYEING KERATIN FIBRES, COMPRISING AT LEAST ONE FREE-RADICAL COMPOUND OF NITROXYL TYPE AND AT LEAST ONE PRIMARY OR SECONDARY ALCOHOL L'OREAL (FR) 2004-07-08 WO claimed
EP-0981319-B1 DYEING HAIR WITH MELANIN PRECURSORS IN THE PRESENCE OF IODATE AND PEROXIDE P & G CLAIROL INC (US) 2003-10-15 EP claimed
EP-1239817-A1 USE OF METHYLCHINOLINIUM COMPOUNDS FOR DYEING KERATIN CONTAINING FIBERS Henkel Kommanditgesellschaft auf Aktien (DE) 2002-09-18 EP claimed
WO-2001047483-A1 USE OF METHYLCHINOLINIUM COMPOUNDS FOR DYEING KERATIN CONTAINING FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-07-05 WO claimed
EP-0603322-B1 DYEING COMPOSITION BASED ON HYDROXYINDOLINE DERIVATIVES OREAL (FR) 1996-12-11 EP claimed
EP-0603322-A1 DYEING COMPOSITION BASED ON HYDROXYINDOLINE DERIVATIVES. OREAL (FR) 1994-06-29 EP claimed
EP-0575605-A1 MINERAL OR ORGANIC PARTICLE BASED PRODUCT COMPRISING AN INDOLINE PRODUCT. OREAL (FR) 1993-12-29 EP claimed
WO-1993013745-A1 MINERAL OR ORGANIC PARTICLE BASED PRODUCT COMPRISING AN INDOLINE PRODUCT L'OREAL (FR) 1993-07-22 WO claimed
WO-1993005018-A1 DYEING COMPOSITION BASED ON HYDROXYINDOLINE DERIVATIVES L'OREAL (FR) 1993-03-18 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12564545-B2 Hair coloring compositions comprising 2-amino-1-propanol as alkalising agents PHOSPHO1, ALDH7A1, AASDHPPT AADAT 4/4885GOT1 952/4885KYAT1 1400/4885
US-12636241-B1 Method and composition for oxidative hair coloring POLB, DAO, ALPP AADAT 21/4885GOT1 239/4885KYAT1 1767/4885
US-20240342067-A1 Hair Coloring Compositions Comprising 2-Amino-1-Propanol As Alkalising Agents ALDH7A1, PTMA, AAAS AADAT 16/4885GOT1 1187/4885KYAT1 1053/4885
US-20260144724-A1 Mixture of at least five surfactants (I1) to (I5) DEGS1, SGMS1, FABP4 AADAT 4169/4885GOT1 1319/4885KYAT1 2198/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.