Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | WDR5 | P61964 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3898987 | 0.82 | MEN1 (0.41) | MGAMWDR5LDHAKDM4EACMSD | |
| SCHEMBL1127740 | 0.82 | ALDH1A1 (0.46) | MGAMTSHRTDP1KMT2AMEN1 | |
| SCHEMBL1181527 | 0.82 | PARP1 (0.41) | MGAMKDM4ETSHRTDP1ALDH1A1 | |
| SCHEMBL758982 | 0.82 | ALDH1A1 (0.38) | MGAMKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL8757247 | 0.78 | RAB9A (0.47) | KDM4ETSHRKMT2AMEN1ALDH1A1 | |
| SCHEMBL3251538 | 0.78 | IDO1 (0.43) | KDM4EKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL2167038 | 0.77 | TSHR (0.42) | KDM4ETSHRKMT2AMEN1ALDH1A1 | |
| SCHEMBL12984354 | 0.77 | SMN1; SMN2 (0.38) | MGAMKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL27719957 | 0.76 | KDM4E (0.42) | KDM4ETSHRTDP1KMT2AMEN1 | |
| SCHEMBL9658676 | 0.76 | ELANE (0.37) | KDM4EALDH1A1CYP1A2SMN1; SMN2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 226 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101925658-B | Anthrapyridone compound or salt thereof, magenta ink composition containing anthrapyridone compound, and colored body | NIPPON KAYAKU KK | 2013-10-02 | — | — | CN | claimed |
| US-8426115-B2 | Patterning process and resist composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2013-04-23 | — | — | US | claimed |
| US-20110033803-A1 | PATTERNING PROCESS AND RESIST COMPOSITION | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2011-02-10 | — | — | US | claimed |
| US-20070015918-A1 | Derivatives of 1,3-diones having a herbicidal activity | ISAGRO RICERCA S.R.L (IT) | 2007-01-18 | — | — | US | claimed |
| EP-1670772-A1 | DERIVATIVES OF 1,3-DIONES HAVING A HERBICIDAL ACTIVITY | Isagro Ricerca S.r.l. (IT) | 2006-06-21 | — | — | EP | claimed |
| EP-0799281-B2 | CARBON BLACK REACTED WITH DIAZONIUM SALTS AND PRODUCTS | CABOT CORP (US) | 2006-03-29 | — | — | EP | claimed |
| US-20060025345-A1 | Substituted ethane-1,2-diamines for the treatment of Alzheimer's disease | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-02-02 | — | — | US | claimed |
| WO-2005113582-A1 | SUBSTITUTED ETHANE-1,2-DIAMINES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-12-01 | — | — | WO | claimed |
| US-6969703-B2 | Inhibitors of the ICE/ced-3 family of cysteine proteases | IDUN PHARMACEUTICALS, INC. (US) | 2005-11-29 | — | — | US | claimed |
| WO-2005030736-A1 | DERIVATIVES OF 1,3-DIONES HAVING A HERBICIDAL ACTIVITY | ISAGRO RICERCA S.R.L. (IT) | 2005-04-07 | — | — | WO | claimed |
| US-6242422-B1 | (Substituted)Acyl dipeptidyl inhibitors of the ice/ced-3 family of cysteine proteases | IDUN PHARMACUETICALS, INC. | 2001-06-05 | — | — | US | claimed |
| WO-2000023421-A1 | (SUBSTITUTED)ACYL DIPEPTIDYL INHIBITORS OF THE ICE/ced-3 FAMILY OF CYSTEINE PROTEASES | IDUN PHARMACEUTICALS, INC. (US) | 2000-04-27 | — | — | WO | claimed |
| US-6042643-A | AS PIGMENT TO COLOR PLASTICS, PAPER, TEXTILE, RUBBER, AQUEOUS INKS | CABOT CORPORATION (US) | 2000-03-28 | — | — | US | claimed |
| US-5900029-A | COLORING FIBER OR TEXTILE | CABOT CORPORATION (US) | 1999-05-04 | — | — | US | claimed |
| EP-0799281-A1 | CARBON BLACK REACTED WITH DIAZONIUM SALTS AND PRODUCTS | CABOT CORPORATION (US) | 1997-10-08 | — | — | EP | claimed |
| WO-1996018688-A1 | CARBON BLACK REACTED WITH DIAZONIUM SALTS AND PRODUCTS | CABOT CORPORATION (US) | 1996-06-20 | — | — | WO | claimed |
| EP-0687249-A1 | BALANOIDS | ELI LILLY AND COMPANY (US) | 1995-12-20 | — | — | EP | claimed |
| WO-1994020062-A2 | BALANOIDS AS PROTEIN KINASE C INHIBITORS | ELI LILLY AND COMPANY (US) | 1994-09-15 | — | — | WO | claimed |
| US-4444875-A | LAYER OF A TETRAZOLIUM COMPOUND | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1984-04-24 | — | — | US | claimed |
| US-4052433-A | INTERMEDIATES FOR BENZOFURANS | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-10-04 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060025345-A1 | Substituted ethane-1,2-diamines for the treatment of Alzheimer's disease | PSEN1, PSEN2, APP | MGAM 3632/4885WDR5 3285/4885LDHA 4271/4885 |
| US-20070015918-A1 | Derivatives of 1,3-diones having a herbicidal activity | DDT, CYP1B1, CYP51A1 | MGAM 198/4885WDR5 1423/4885LDHA 1317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.