SCHEMBL758982

SCHEMBL758982

CC(=O)c1[c]c2ccccc2cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.38
MAPT P10636 3/20 0.38
HPGD P15428 2/20 0.38
MGAM O43451 1/20 0.33
KDM4E B2RXH2 4/20 0.33
SMN1; SMN2 Q16637 4/20 0.33
CYP1A2 P05177 3/20 0.33
MAOB P27338 2/20 0.33
CA12 O43570 1/20 0.33
NT5E P21589 1/20 0.33
CA9 Q16790 1/20 0.33
CES2 O00748 2/20 0.32
CES1 P23141 2/20 0.32
NOTUM Q6P988 1/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
NCEH1 Q6PIU2 1/20 0.32
CYP2C19 P33261 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1128018 0.83 ALDH1A1 (0.39) ALDH1A1MAPTHPGDKDM4ESMN1; SMN2
SCHEMBL49732 0.82 MGAM (0.42) ALDH1A1MAPTHPGDMGAMKDM4E
SCHEMBL11645110 0.80 ALDH1A1 (0.51) ALDH1A1MAPTHPGDKDM4EMAOB
SCHEMBL1181527 0.80 PARP1 (0.41) ALDH1A1MAPTHPGDMGAMKDM4E
SCHEMBL12984354 0.79 SMN1; SMN2 (0.38) ALDH1A1MAPTHPGDMGAMKDM4E
SCHEMBL2167038 0.79 TSHR (0.42) ALDH1A1MAPTHPGDKDM4ECA12
SCHEMBL9658680 0.78 ELANE (0.37) ALDH1A1KDM4ESMN1; SMN2CYP1A2RAB9A
SCHEMBL9658676 0.78 ELANE (0.37) ALDH1A1KDM4ESMN1; SMN2CYP1A2RAB9A
SCHEMBL1127740 0.77 ALDH1A1 (0.46) ALDH1A1MAPTMGAMCES2CES1
SCHEMBL7883312 0.77 SMN1; SMN2 (0.41) ALDH1A1MAPTHPGDKDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 188 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11150555-B2 Photoacid generator and chemically amplified positive-type photoresist composition for thick film comprising the same LG CHEM, LTD. (KR) 2021-10-19 US claimed
US-20200033724-A1 PHOTOACID GENERATOR AND CHEMICALLY AMPLIFIED POSITIVE-TYPE PHOTORESIST COMPOSITION FOR THICK FILM COMPRISING THE SAME LG CHEM, LTD. (KR) 2020-01-30 US claimed
US-7867631-B2 Fluorine-containing compound and organic light-emitting device employing the same SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2011-01-11 US claimed
US-20080169755-A1 FLUORINE-CONTAINING COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE EMPLOYING THE SAME SAMSUNG SDI CO., LTD. (KR) 2008-07-17 US claimed
US-20080132562-A1 TETRONIC AND TETRAMIC ACIDS GODEL THIERRY 2008-06-05 US claimed
EP-1689729-A1 TETRONIC AND TETRAMIC ACIDS AS INHIBITORS OF BETA-SECREASE F. Hoffmann-La Roche AG (CH) 2006-08-16 EP claimed
WO-2005058857-A1 TETRONIC AND TETRAMIC ACIDS AS INHIBITORS OF BETA-SECREASE F. HOFFMANN-LA ROCHE AG (CH) 2005-06-30 WO claimed
US-20050119329-A1 Tetronic and tetramic acids HOFFMANN-LA ROCHE INC. 2005-06-02 US claimed
EP-0966456-B1 TAXOID REVERSAL AGENTS FOR DRUG-RESISTANCE IN CANCER CHEMOTHERAPY AND PHARMACEUTICAL COMPOSITIONS THEREOF UNIV NEW YORK STATE RES FOUND (US) 2003-04-02 EP claimed
US-6158488-A Rubber composition containing modified carbon black and article having component thereof THE GOODYEAR TIRE & RUBBER COMPANY (US) 2000-12-12 US claimed
EP-0966456-A4 TAXOID REVERSAL AGENTS FOR DRUG-RESISTANCE IN CANCER CHEMOTHERAPY AND PHARMACEUTICAL COMPOSITIONS THEREOF RES FOUNDATION OF (US) 2000-07-26 EP claimed
CN-1250789-A Rubber compositions contg. modified carbon black, and parts products made therewith GOODYEAR TIRE & RUBBER (US) 2000-04-19 CN claimed
EP-0992535-A1 Rubber composition containing silanol modified carbon black THE GOODYEAR TIRE & RUBBER COMPANY (US) 2000-04-12 EP claimed
EP-0966456-A1 TAXOID REVERSAL AGENTS FOR DRUG-RESISTANCE IN CANCER CHEMOTHERAPY AND PHARMACEUTICAL COMPOSITIONS THEREOF THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1999-12-29 EP claimed
US-5811452-A ADMINISTERING WITH PACLITAXEL OR DOXORUBICIN THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1998-09-22 US claimed
WO-1998030553-A1 TAXOID REVERSAL AGENTS FOR DRUG-RESISTANCE IN CANCER CHEMOTHERAPY AND PHARMACEUTICAL COMPOSITIONS THEREOF THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1998-07-16 WO claimed
US-20240158441-A1 BRANCHED PEPTIDES FOR ENZYMATIC ASSEMBLY AND MITOCHONDRIA DRUG DELIVERY NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2024-05-16 US disclosed
US-20240045330-A1 NEGATIVE PHOTOSENSITIVE COMPOSITION AND PATTERN FORMATION METHOD TOKYO OHKA KOGYO CO., LTD. (JP) 2024-02-08 US disclosed
US-4076537-A Light-sensitive materials containing organo tellurium or selenium compounds and sensitizers FUJI PHOTO FILM CO., LTD. (JA) 1978-02-28 US disclosed
US-4062685-A ORGANO-TELLURIUM COMPOUND FUJI PHOTO FILM CO., LTD. (JA) 1977-12-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200033724-A1 PHOTOACID GENERATOR AND CHEMICALLY AMPLIFIED POSITIVE-TYPE PHOTORESIST COMPOSITION FOR THICK FILM COMPRISING THE SAME ASIC1, PPA1, ATP6AP1 ALDH1A1 3269/4885MAPT 799/4885HPGD 2315/4885
US-20080132562-A1 TETRONIC AND TETRAMIC ACIDS BACE1, PSEN1, BACE2 ALDH1A1 2826/4885MAPT 74/4885HPGD 4570/4885
US-20050119329-A1 Tetronic and tetramic acids BACE1, PSEN1, BACE2 ALDH1A1 2826/4885MAPT 74/4885HPGD 4570/4885
US-20080169755-A1 FLUORINE-CONTAINING COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE EMPLOYING THE SAME SLC43A1, FEM1B, KCNH3 ALDH1A1 1121/4885MAPT 2812/4885HPGD 4543/4885
US-11150555-B2 Photoacid generator and chemically amplified positive-type photoresist composition for thick film comprising the same ASIC1, PPA1, ATP6AP1 ALDH1A1 3269/4885MAPT 799/4885HPGD 2315/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.