Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | CCR3 | P51677 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4180052 | 1.00 | HRH3 (0.45) | HRH3GAASIGMAR1ACHEGBA1 | |
| SCHEMBL4190627 | 0.84 | ROCK2 (0.44) | — | |
| SCHEMBL7003079 | 0.66 | SLC6A3 (0.61) | HRH3SIGMAR1ACHEGBA1CCR3 | |
| SCHEMBL7692425 | 0.66 | SLC18A2 (0.56) | HRH3GAASIGMAR1 | |
| SCHEMBL7695964 | 0.66 | SLC18A2 (0.56) | HRH3GAASIGMAR1 | |
| SCHEMBL24493725 | 0.66 | ACHE (0.51) | HRH3GAASIGMAR1ACHE | |
| SCHEMBL7383573 | 0.65 | HRH3 (0.58) | HRH3SIGMAR1ACHEGBA1CCR3 | |
| SCHEMBL7385498 | 0.65 | HRH3 (0.58) | HRH3SIGMAR1ACHEGBA1CCR3 | |
| SCHEMBL5375336 | 0.65 | GAA (0.59) | HRH3GAASIGMAR1GBA1 | |
| SCHEMBL5556346 | 0.65 | GAA (0.59) | HRH3GAASIGMAR1GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1968980-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES, LTD. (IN) | 2008-09-17 | — | — | EP | disclosed |
| WO-2007110782-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-10-04 | — | — | WO | disclosed |