SCHEMBL4979808

SCHEMBL4979808

NC(=O)NC(=O)CCC(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PHF8 Q9UPP1 6/20 0.56
KDM2A Q9Y2K7 6/20 0.56
KDM4E B2RXH2 4/20 0.56
KDM5C P41229 4/20 0.56
EGLN1 Q9GZT9 5/20 0.52
KDM6B O15054 2/20 0.52
FOLH1 Q04609 1/20 0.52
LMNA P02545 2/20 0.47
ALKBH5 Q6P6C2 1/20 0.47
SUCNR1 Q9BXA5 1/20 0.47
KDM7A Q6ZMT4 1/20 0.44
GABRR1 P24046 1/20 0.40
ALDH1A1 P00352 1/20 0.39
CYP1A2 P05177 1/20 0.38
TSHR P16473 1/20 0.38
NFKB1 P19838 1/20 0.38
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
THPO P40225 1/20 0.38
CYP1A1 P04798 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Succinic Acid SCHEMBL28081664 0.86 LMNA (0.56) PHF8KDM2AKDM4EKDM5CEGLN1
SCHEMBL4975748 0.85 SLC22A6 (0.52) PHF8KDM2AKDM4EKDM5CLMNA
SCHEMBL4978244 0.80 PHF8 (0.52) PHF8KDM2AKDM4EKDM5CEGLN1
SCHEMBL4977758 0.80 PHF8 (0.52) PHF8KDM2AKDM4EKDM5CEGLN1
Glycine SCHEMBL16637330 0.79 PHF8 (0.56) PHF8KDM2AKDM4EKDM5CEGLN1
SCHEMBL27487678 0.78 LDHA (0.44) PHF8KDM2AKDM4EKDM5CEGLN1
SCHEMBL28461081 0.78 PHF8 (0.57) PHF8KDM2AKDM4EKDM5CEGLN1
SCHEMBL4977396 0.78 PHF8 (0.57) PHF8KDM2AKDM4EKDM5CEGLN1
SCHEMBL11590030 0.77 ALDH1A1 (0.50) PHF8KDM2AKDM4EKDM5CEGLN1
SCHEMBL28712925 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1685114-B1 ANTIBACTERIAL AND/OR ANTIPROTOZOAL NITROIMIDAZOLE DERIVATIVE COMPOUNDS WITH UREASE INHIBITOR ACTIVITY, PROCESS FOR PREPARING THESE COMPOUNDS AND USE IN PHARMACEUTICAL COMPOSITIONS AND MEDICINES. EMS SA (BR) 2008-10-15 EP claimed
US-20240099955-A1 SKINCARE COMPOSITIONS AND METHODS OF USE THEREOF HTL BIOTECHNOLOGY INNOVATION INC. 2024-03-28 US disclosed
EP-4288084-A1 SKINCARE COMPOSITIONS AND METHODS OF USE THEREOF Modern Meadow, Inc. (US) 2023-12-13 EP disclosed
WO-2022170114-A1 SKINCARE COMPOSITIONS AND METHODS OF USE THEREOF MODERN MEADOW, INC. (US) 2022-08-11 WO disclosed
WO-2019002842-A1 BICYCLIC PEPTIDE LIGANDS WITH DETECTABLE MOIETIES AND USES THEREOF Bicyclerd Limited (GB) 2019-01-03 WO disclosed
US-5292451-A For bleaching, oxidizing, or disinfecting HOECHST AKTIENGESELLSCHAFT (DE) 1994-03-08 US disclosed
US-5149864-A Oxidation of uridocaroxylic acid derivative with hydrogen peroxide in presence of strong acidic catalyst HOECHST AKTIENGESELLSCHAFT (DE) 1992-09-22 US disclosed