SCHEMBL4975784

SCHEMBL4975784

C=C(C)C(=O)OC(OC(=O)CCC(=O)OC(OC(=O)C(=C)C)C(C)O)C(C)O

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.41
ALDH1A1 P00352 2/20 0.37
LMNA P02545 3/20 0.32
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27481368 0.93 TSHR (0.37) TSHRALDH1A1LMNA
SCHEMBL4980922 0.93 LMNA (0.41) TSHRALDH1A1LMNA
SCHEMBL4975150 0.91 LMNA (0.43) TSHRALDH1A1LMNA
SCHEMBL649529 0.88 TSHR (0.45) TSHRALDH1A1THRB
SCHEMBL27466370 0.87 TSHR (0.37) TSHRALDH1A1LMNA
SCHEMBL245323 0.86 LMNA (0.54) TSHRALDH1A1LMNA
SCHEMBL245004 0.86 LMNA (0.54) TSHRALDH1A1LMNA
SCHEMBL245029 0.86 LMNA (0.54) TSHRALDH1A1LMNA
SCHEMBL11477473 0.80 TSHR (0.42) TSHRALDH1A1THRB
SCHEMBL3360326 0.79 TSHR (0.42) TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080015272-A1 Polyurethane Foam FRITZ NAUER AG (CH) 2008-01-17 US disclosed
EP-1817358-A1 POLYURETHANE FOAM Fritz Nauer AG (CH) 2007-08-15 EP disclosed
US-7132459-B1 Moulded bodies made from a polyurethane material, production and use thereof FRITZ NAUER AG (CH) 2006-11-07 US disclosed
WO-2006056485-A1 POLYURETHANE FOAM FRITZ NAUER AG. (CH) 2006-06-01 WO disclosed